Gastric necrosis in newborns: A report of 11 cases

G. Pelizzo, R. Dubois, A. Lapillonne, X. Lainé, O. Claris, R. Bouvier, J. P. Chappuis

Research output: Contribution to journalArticlepeer-review


Eleven neonates ranging in gestational age from 34 to 40 weeks presented with gastric necrosis. The 4 full-term neonates showed sudden-onset hemorrage and 'coffee-ground' vomiting; in the 7 premature babies the initial clinical finding was abdominal distention. The criteria for diagnosis were: perinatal distress in prematures and transient neonatal respiratory distress in full-term babies. Radiographic evidence of gastric distention was typical and preceded clinical signs of hematemesis and gastric perforation. Surgery was performed in 8 patients; 3 received medical treatment. At surgery 1 total and 3 subtotal gastrectomies and 4 segmental gastric resections were performed. Three of these patients died post-operatively as a consequence of multiorgan failure; a second look was necessary in one patient 1 week after surgery because of prepyloric perforation due to ulcers. Biopsy specimens taken from the site of perforation demonstrated extensive necrosis; ulceration was disseminated in the surrounding gastric mucosa; no signs of phlogosis were detected. The diagnosis, treatment, and physiopathologic considerations are reviewed.

Original languageEnglish
Pages (from-to)346-349
Number of pages4
JournalPediatric Surgery International
Issue number5-6
Publication statusPublished - Jul 1998


  • Gastric infarction
  • Gastric necrosis
  • Neonatal gastric perforation
  • Peptic ulcer disease in children
  • Spontaneous gastric perforation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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