Abstract
Eleven neonates ranging in gestational age from 34 to 40 weeks presented with gastric necrosis. The 4 full-term neonates showed sudden-onset hemorrage and 'coffee-ground' vomiting; in the 7 premature babies the initial clinical finding was abdominal distention. The criteria for diagnosis were: perinatal distress in prematures and transient neonatal respiratory distress in full-term babies. Radiographic evidence of gastric distention was typical and preceded clinical signs of hematemesis and gastric perforation. Surgery was performed in 8 patients; 3 received medical treatment. At surgery 1 total and 3 subtotal gastrectomies and 4 segmental gastric resections were performed. Three of these patients died post-operatively as a consequence of multiorgan failure; a second look was necessary in one patient 1 week after surgery because of prepyloric perforation due to ulcers. Biopsy specimens taken from the site of perforation demonstrated extensive necrosis; ulceration was disseminated in the surrounding gastric mucosa; no signs of phlogosis were detected. The diagnosis, treatment, and physiopathologic considerations are reviewed.
| Original language | English |
|---|---|
| Pages (from-to) | 346-349 |
| Number of pages | 4 |
| Journal | Pediatric Surgery International |
| Volume | 13 |
| Issue number | 5-6 |
| DOIs | |
| Publication status | Published - Jul 1998 |
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Keywords
- Gastric infarction
- Gastric necrosis
- Neonatal gastric perforation
- Peptic ulcer disease in children
- Spontaneous gastric perforation
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Gastric necrosis in newborns : A report of 11 cases. / Pelizzo, G.; Dubois, R.; Lapillonne, A.; Lainé, X.; Claris, O.; Bouvier, R.; Chappuis, J. P.
In: Pediatric Surgery International, Vol. 13, No. 5-6, 07.1998, p. 346-349.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gastric necrosis in newborns
T2 - A report of 11 cases
AU - Pelizzo, G.
AU - Dubois, R.
AU - Lapillonne, A.
AU - Lainé, X.
AU - Claris, O.
AU - Bouvier, R.
AU - Chappuis, J. P.
PY - 1998/7
Y1 - 1998/7
N2 - Eleven neonates ranging in gestational age from 34 to 40 weeks presented with gastric necrosis. The 4 full-term neonates showed sudden-onset hemorrage and 'coffee-ground' vomiting; in the 7 premature babies the initial clinical finding was abdominal distention. The criteria for diagnosis were: perinatal distress in prematures and transient neonatal respiratory distress in full-term babies. Radiographic evidence of gastric distention was typical and preceded clinical signs of hematemesis and gastric perforation. Surgery was performed in 8 patients; 3 received medical treatment. At surgery 1 total and 3 subtotal gastrectomies and 4 segmental gastric resections were performed. Three of these patients died post-operatively as a consequence of multiorgan failure; a second look was necessary in one patient 1 week after surgery because of prepyloric perforation due to ulcers. Biopsy specimens taken from the site of perforation demonstrated extensive necrosis; ulceration was disseminated in the surrounding gastric mucosa; no signs of phlogosis were detected. The diagnosis, treatment, and physiopathologic considerations are reviewed.
AB - Eleven neonates ranging in gestational age from 34 to 40 weeks presented with gastric necrosis. The 4 full-term neonates showed sudden-onset hemorrage and 'coffee-ground' vomiting; in the 7 premature babies the initial clinical finding was abdominal distention. The criteria for diagnosis were: perinatal distress in prematures and transient neonatal respiratory distress in full-term babies. Radiographic evidence of gastric distention was typical and preceded clinical signs of hematemesis and gastric perforation. Surgery was performed in 8 patients; 3 received medical treatment. At surgery 1 total and 3 subtotal gastrectomies and 4 segmental gastric resections were performed. Three of these patients died post-operatively as a consequence of multiorgan failure; a second look was necessary in one patient 1 week after surgery because of prepyloric perforation due to ulcers. Biopsy specimens taken from the site of perforation demonstrated extensive necrosis; ulceration was disseminated in the surrounding gastric mucosa; no signs of phlogosis were detected. The diagnosis, treatment, and physiopathologic considerations are reviewed.
KW - Gastric infarction
KW - Gastric necrosis
KW - Neonatal gastric perforation
KW - Peptic ulcer disease in children
KW - Spontaneous gastric perforation
UR - http://www.scopus.com/inward/record.url?scp=0031799161&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031799161&partnerID=8YFLogxK
U2 - 10.1007/s003830050335
DO - 10.1007/s003830050335
M3 - Article
C2 - 9639613
AN - SCOPUS:0031799161
VL - 13
SP - 346
EP - 349
JO - Pediatric Surgery International
JF - Pediatric Surgery International
SN - 0179-0358
IS - 5-6
ER -