I tumori neuroendocrini del tratto gastro-entero-pancreatico

Translated title of the contribution: Gastroenteropancreatic neuroendocrine tumors

Sara Massironi, Dario Conte, Maddalena Peracchi

Research output: Contribution to journalArticlepeer-review


Gastroenteropancreatic (GEP) neuroendocrine tumors (NETs) are rare neoplasms. They are varied in their biological and clinical behavior: most have endocrine function and they secrete peptides that cause distinct clinical syndromes, including carcinoid syndrome; many are clinically silent until late presentation. Investigation and management should be individualized for each patient, taking into consideration the natural history of the tumour and general health of the patient. Management strategies include surgery and other cytoreductive techniques for cure and palliation and medical treatment including chemotherapy and biotherapy (somatostatin analogues and alpha-inteferon) to control symptoms and tumor growth. New biological agents and peptide receptor radionuclide therapy are under investigation.

Translated title of the contributionGastroenteropancreatic neuroendocrine tumors
Original languageItalian
Pages (from-to)41-48
Number of pages8
JournalArgomenti di Gastroenterologia Clinica
Issue number2
Publication statusPublished - Jun 2008

ASJC Scopus subject areas

  • Gastroenterology


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