Gastrointestinal bleeding from enterically drained transplanted pancreas

Elena Orsenigo, Paolo Fiorina, Giacomo Dell'Antonio, Marco Cristallo, Carlo Socci, Laura Invernizzi, Paola Maffi, Antonio Secchi, Valerio Di Carlo

Research output: Contribution to journalArticle

Abstract

Gastrointestinal bleeding has been described as related complication of pancreas transplantation. Of 166 simultaneous pancreas kidney transplantations, 61 were enteric-drained pancreas transplants (eight done with and 53 without Roux-en-Y loop). The patients were divided into two groups according to Roux (group I, n = 8) or no Roux (group II, n = 53) technique. Seven patients experienced anastomotic hemorrhage between the jejunum and duodenal stump (11%), five cases in group I and two in group II (P <0.001). No relationships between gastrointestinal bleeding duodenal stump and recipient jejunum blood flow, mean pancreatic cold ischemia time, platelet count, and prothrombin time were observed. Donor age over 40 years and abnormal activated partial thromboplastin time constituted risk factors for hemorrhage from the duodenojejunal anastomosis. There were no significant differences in pancreas graft and patient survival rates between the two groups. Anastomotic hemorrhage did not influence patient and graft survival.

Original languageEnglish
Pages (from-to)296-302
Number of pages7
JournalTransplant International
Volume18
Issue number3
DOIs
Publication statusPublished - Mar 2005

Keywords

  • Enteric drainage
  • Gastrointestinal bleeding
  • Laser-Doppler flowmetry
  • Pancreas transplantation

ASJC Scopus subject areas

  • Transplantation

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