Gastrointestinal involvement in children with SARS-COV-2 infection: An overview for the pediatrician

Elena Chiappini, Amelia Licari, Marco Antonio Motisi, Sara Manti, Gian Luigi Marseglia, Luisa Galli, Paolo Lionetti

Research output: Contribution to journalArticlepeer-review


Gastrointestinal symptoms are common findings in children with SARS-CoV-2 infection. Diarrhea and vomiting have been reported in about 8%-9% of cases, reaching more than 20% in some studies. Children with gastrointestinal involvement appear to be younger than those without, but the severity of the disease seems to be similar between the two groups of subjects. Fecal shedding in children has been reported in 20%-30% of children and has been observed in both those with and those without overt gastrointestinal involvement. Moreover, prolonged fecal elimination, lasting several days after negativization of real-time polymerase chain reaction assay on respiratory swabs, has been reported with variable frequency in children with SARS-CoV-2 infection. These observations raise the question regarding the possibility of oral-fecal transmission and the possible role of children in spreading the infection, particularly when they appear asymptomatic or with gastrointestinal symptoms but with no respiratory involvement, as well as during their convalescent phase.

Original languageEnglish
Pages (from-to)92-95
Number of pages4
JournalPediatric Allergy and Immunology
Issue numberS26
Publication statusPublished - Nov 2020


  • children
  • COVID-19
  • gastrointestinal symptoms
  • SARS-CoV-2

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Immunology


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