Gastrointestinal motility disorders in patients with inactive Crohn's disease

V. Annese, G. Bassotti, G. Napolitano, P. Usai, A. Andriulli, G. Vantrappen

Research output: Contribution to journalArticle

107 Citations (Scopus)

Abstract

Background: Although some symptoms of Crohn's disease may be related to gastrointestinal motility disorders, studies on gastrointestinal motility in inactive Crohn's disease are lacking. Methods: Fasting and postprandial motor activity (1 h) was recorded in the gastric antrum and upper small intestine of 35 patients with inactive Crohn's disease and 18 controls, using conventional manometry. Results: Motor disorders were observed in 26 of 35 patients. The number of phase-II contractions was reduced (1.3 ± 0.7/min versus 1.8 ± 0.6/min in controls; P <0.02) (mean ± standard deviation), whereas the incidence of propagated single (2.2 ± 3.2/h versus 0.5 ± 0.6/h; P <0.03) and clustered contractions (3.8 ± 7/h versus 1.1 ± 1.4, P <0.04) was markedly increased. Motor abnormalities were more frequent and severe in patients with Crohn's ileitis than in controls, and in patients with gastrointestinal symptoms than in asymptomatic patients. Conclusion: Most patients with inactive, uncomplicated Crohn's disease show marked gastrointestinal motor disorders, characterized either by reduced incidence of small-bowel contractions and increased incidence of single or clustered propagated contractions.

Original languageEnglish
Pages (from-to)1107-1117
Number of pages11
JournalScandinavian Journal of Gastroenterology
Volume32
Issue number11
Publication statusPublished - 1997

Fingerprint

Gastrointestinal Motility
Crohn Disease
Incidence
Ileitis
Pyloric Antrum
Manometry
Small Intestine
Fasting
Motor Activity

Keywords

  • Crohn's disease
  • Gastrointestinal
  • Manometry
  • Motility

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Annese, V., Bassotti, G., Napolitano, G., Usai, P., Andriulli, A., & Vantrappen, G. (1997). Gastrointestinal motility disorders in patients with inactive Crohn's disease. Scandinavian Journal of Gastroenterology, 32(11), 1107-1117.

Gastrointestinal motility disorders in patients with inactive Crohn's disease. / Annese, V.; Bassotti, G.; Napolitano, G.; Usai, P.; Andriulli, A.; Vantrappen, G.

In: Scandinavian Journal of Gastroenterology, Vol. 32, No. 11, 1997, p. 1107-1117.

Research output: Contribution to journalArticle

Annese, V, Bassotti, G, Napolitano, G, Usai, P, Andriulli, A & Vantrappen, G 1997, 'Gastrointestinal motility disorders in patients with inactive Crohn's disease', Scandinavian Journal of Gastroenterology, vol. 32, no. 11, pp. 1107-1117.
Annese, V. ; Bassotti, G. ; Napolitano, G. ; Usai, P. ; Andriulli, A. ; Vantrappen, G. / Gastrointestinal motility disorders in patients with inactive Crohn's disease. In: Scandinavian Journal of Gastroenterology. 1997 ; Vol. 32, No. 11. pp. 1107-1117.
@article{839ba5c304f841ed93c3132704fd8743,
title = "Gastrointestinal motility disorders in patients with inactive Crohn's disease",
abstract = "Background: Although some symptoms of Crohn's disease may be related to gastrointestinal motility disorders, studies on gastrointestinal motility in inactive Crohn's disease are lacking. Methods: Fasting and postprandial motor activity (1 h) was recorded in the gastric antrum and upper small intestine of 35 patients with inactive Crohn's disease and 18 controls, using conventional manometry. Results: Motor disorders were observed in 26 of 35 patients. The number of phase-II contractions was reduced (1.3 ± 0.7/min versus 1.8 ± 0.6/min in controls; P <0.02) (mean ± standard deviation), whereas the incidence of propagated single (2.2 ± 3.2/h versus 0.5 ± 0.6/h; P <0.03) and clustered contractions (3.8 ± 7/h versus 1.1 ± 1.4, P <0.04) was markedly increased. Motor abnormalities were more frequent and severe in patients with Crohn's ileitis than in controls, and in patients with gastrointestinal symptoms than in asymptomatic patients. Conclusion: Most patients with inactive, uncomplicated Crohn's disease show marked gastrointestinal motor disorders, characterized either by reduced incidence of small-bowel contractions and increased incidence of single or clustered propagated contractions.",
keywords = "Crohn's disease, Gastrointestinal, Manometry, Motility",
author = "V. Annese and G. Bassotti and G. Napolitano and P. Usai and A. Andriulli and G. Vantrappen",
year = "1997",
language = "English",
volume = "32",
pages = "1107--1117",
journal = "Scandinavian Journal of Gastroenterology",
issn = "0036-5521",
publisher = "Informa Healthcare",
number = "11",

}

TY - JOUR

T1 - Gastrointestinal motility disorders in patients with inactive Crohn's disease

AU - Annese, V.

AU - Bassotti, G.

AU - Napolitano, G.

AU - Usai, P.

AU - Andriulli, A.

AU - Vantrappen, G.

PY - 1997

Y1 - 1997

N2 - Background: Although some symptoms of Crohn's disease may be related to gastrointestinal motility disorders, studies on gastrointestinal motility in inactive Crohn's disease are lacking. Methods: Fasting and postprandial motor activity (1 h) was recorded in the gastric antrum and upper small intestine of 35 patients with inactive Crohn's disease and 18 controls, using conventional manometry. Results: Motor disorders were observed in 26 of 35 patients. The number of phase-II contractions was reduced (1.3 ± 0.7/min versus 1.8 ± 0.6/min in controls; P <0.02) (mean ± standard deviation), whereas the incidence of propagated single (2.2 ± 3.2/h versus 0.5 ± 0.6/h; P <0.03) and clustered contractions (3.8 ± 7/h versus 1.1 ± 1.4, P <0.04) was markedly increased. Motor abnormalities were more frequent and severe in patients with Crohn's ileitis than in controls, and in patients with gastrointestinal symptoms than in asymptomatic patients. Conclusion: Most patients with inactive, uncomplicated Crohn's disease show marked gastrointestinal motor disorders, characterized either by reduced incidence of small-bowel contractions and increased incidence of single or clustered propagated contractions.

AB - Background: Although some symptoms of Crohn's disease may be related to gastrointestinal motility disorders, studies on gastrointestinal motility in inactive Crohn's disease are lacking. Methods: Fasting and postprandial motor activity (1 h) was recorded in the gastric antrum and upper small intestine of 35 patients with inactive Crohn's disease and 18 controls, using conventional manometry. Results: Motor disorders were observed in 26 of 35 patients. The number of phase-II contractions was reduced (1.3 ± 0.7/min versus 1.8 ± 0.6/min in controls; P <0.02) (mean ± standard deviation), whereas the incidence of propagated single (2.2 ± 3.2/h versus 0.5 ± 0.6/h; P <0.03) and clustered contractions (3.8 ± 7/h versus 1.1 ± 1.4, P <0.04) was markedly increased. Motor abnormalities were more frequent and severe in patients with Crohn's ileitis than in controls, and in patients with gastrointestinal symptoms than in asymptomatic patients. Conclusion: Most patients with inactive, uncomplicated Crohn's disease show marked gastrointestinal motor disorders, characterized either by reduced incidence of small-bowel contractions and increased incidence of single or clustered propagated contractions.

KW - Crohn's disease

KW - Gastrointestinal

KW - Manometry

KW - Motility

UR - http://www.scopus.com/inward/record.url?scp=0030781103&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030781103&partnerID=8YFLogxK

M3 - Article

C2 - 9399391

AN - SCOPUS:0030781103

VL - 32

SP - 1107

EP - 1117

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

SN - 0036-5521

IS - 11

ER -