Although polyposis syndromes contribute to approximately 1% of the total burden of GI cancers, their scientific and clinical interest is relevant. In the last few years significant advances in the study of molecular basis of familial adenomatous polyposis (FAP) and hereditary flat adenoma syndrome are giving us new insights in the genetic pathways leading to colorectal cancer. Moreover, the knowledge of the clinical features of adenomatous and amarthomatous polyposis syndromes is changing; in fact, extracolonic manifestations of FAP are even more accurately defined and the malignancy potential of juvenile polyposis and Peutz-Jeghers syndrome is emerging more clearly. The authors are presenting here a review of the best international literature of the years 1992-1993 concerning these items.
|Translated title of the contribution||Gastrointestinal polyposis|
|Number of pages||7|
|Journal||Giornale Italiano di Endoscopia Digestiva|
|Publication status||Published - 1995|
ASJC Scopus subject areas