Tumore stromale gastrointestinale del pancreas: Caso clinico e revisione della letteratura

Translated title of the contribution: Gastrointestinal stromal tumor of the pancreas: A case report and review of the literature

Serena Bertozzi, Ambrogio P. Londero, Vittorio Cherchi, Stefania Basso, Vincenzo Canzonieri, Stefano Bacchetti, Alessandro Uzzau

Research output: Contribution to journalArticle

Abstract

Gastrointestinal stromal tumours (GIST) represent a rare borderline neoplastic disease, which is currently thought to arise from the interstitial cells of Cajal, very few cases of pancreatic GIST having been reported so far. We report a case of a 60 year-old man with an incidental imaging (MRI) finding of a solid mass in the pancreatic head, which histological examination revealed to be a GIST. The patient had a disease recurrence after 42 months, received systemic treatment with Imatinib with benefit, and is still alive 53 months after diagnosis with a good quality of life. Although the studies published on pancreatic GIST are rare, we agree with most authors that GIST should always be considered in the differential diagnosis of a solid pancreatic mass, and a preoperative histological diagnosis possibly supported by intraoperative histological confirmation may be remarkably useful in order to tailor the surgical approach. Finally, despite its high risk, pancreatic GIST does not imply a poor prognosis if correctly treated by loco-regional surgical excision: its course depends on handling any complications of major abdominal surgery, which may be very serious in the case of the pancreatic localization.

Translated title of the contributionGastrointestinal stromal tumor of the pancreas: A case report and review of the literature
Original languageItalian
Pages (from-to)62-69
Number of pages8
JournalEuropean Journal of Oncology
Volume19
Issue number1
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Oncology

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    Bertozzi, S., Londero, A. P., Cherchi, V., Basso, S., Canzonieri, V., Bacchetti, S., & Uzzau, A. (2014). Tumore stromale gastrointestinale del pancreas: Caso clinico e revisione della letteratura. European Journal of Oncology, 19(1), 62-69.