Gastrointestinal stromal tumors (GIST) in children and adolescents: A comprehensive review of the current literature

Martin Benesch, Eva Wardelmann, Andrea Ferrari, Bernadette Brennan, Arnauld Verschuur

Research output: Contribution to journalArticle

Abstract

Standards for the management of gastrointestinal stromal tumors (GIST) in children do presently not exist. Thus a systematic review and summary of the current literature was conducted serving as a basis for the further development of optimal management strategies for childhood GIST within a cooperative network. Presently 21 cases with familial GIST, and more than 100 pediatric cases each with Carney triad or sporadic GIST have been published so far. An international prospective registration based on national registries has recently started to acquire more clinical and molecular data and to develop appropriate management strategies for children and adolescents with GIST.

Original languageEnglish
Pages (from-to)1171-1179
Number of pages9
JournalPediatric Blood and Cancer
Volume53
Issue number7
DOIs
Publication statusPublished - Dec 15 2009

Keywords

  • Adolescents
  • Carney triad
  • Children
  • GIST

ASJC Scopus subject areas

  • Medicine(all)
  • Hematology
  • Oncology
  • Pediatrics, Perinatology, and Child Health

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