Aim. Gastrointestinal stromal tumours (GISTs) represent one of the emerging topics in oncology. Although traditionally considered unusual tumours, their incidence is constantly growing. The aim of the present study is to evaluate the real prevalence of GISTs in previous surgical case records, according to modern diagnostic and prognostic criteria. Materials and methods. The retrospective survey was conducted on the surgical cases observed in the period 1981-2002. Twenty-four gastrointestinal and/or abdominal mesenchymal neoplasms were identified, three of which were originally diagnosed as GIST. These latter diagnoses were concentrated in the period 2001-2002 and contained indication of malignancy potential in one case. Results. The histologic reappraisal has allowed the recognition of 11 GISTs, confirmed by immunohistochemistry and distributed over the whole period. Conclusions. Our results show that the prevalence of GISTs in previous surgical case records is greater than commonly estimated. The retrospective survey has allowed us to correctly classify the lesions diagnosed in past, and has proved to be a useful training in the diagnosis of gastrointestinal non-epithelial lesions. Such acquisitions provide an important contribution toward a correct epidemiologic classification of GISTs and represent the basis for an effective multidisciplinary approach to the patient.
|Translated title of the contribution||Gastrointestinal stromal tumours (GIST). A retrospective survey of surgical cases|
|Number of pages||7|
|Journal||European Journal of Oncology|
|Publication status||Published - Sep 2004|
ASJC Scopus subject areas
- Cancer Research