GeCo++: A C++ library for genomic features computation and annotation in the presence of variants

Matteo Cereda, Manuela Sironi, Matteo Cavalleri, Uberto Pozzoli

Research output: Contribution to journalArticlepeer-review

Abstract

Summary: We propose a C++ class library developed to the purpose of making the implementation of sequence analysis algorithms easier and faster when genomic annotations and variations need to be considered. The library provides a class hierarchy to seamlessly bind together annotations of genomic elements to sequences and to algorithm results; it allows to evaluate the effect of mutations/variations in terms of both element position shifts and of algorithm results, limiting recalculation to the minimum. Particular care has been posed to keep memory and time overhead into acceptable limits.

Original languageEnglish
Article numberbtr123
Pages (from-to)1313-1315
Number of pages3
JournalBioinformatics
Volume27
Issue number9
DOIs
Publication statusPublished - May 2011

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Computational Theory and Mathematics
  • Computer Science Applications
  • Computational Mathematics
  • Statistics and Probability
  • Medicine(all)

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