Gene-markers representation for microarray data integration

Elena Baralis, Elisa Ficarra, Alessandro Fiori, Enrico Macii

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

When analyzing the relationship between genes under different scenarios, the integration of different microarray experiments becomes a relevant task. This paper presents a framework to address some intrinsic problems of integration, due for instance to scaling issues, error bias, different experimental conditions or technology and protocols. Our approach projects original microarray data in a common transformed space to create a common representation of different microarray datasets. This approach allows us to integrate data from various microarray platforms or microarrays based on different experimental conditions. We validate our framework with experiments on real microarray datasets. The results suggest that our approach can be a profitably exploited for microarray data integration and further gene expression analysis applications.

Original languageEnglish
Title of host publicationProceedings of the 7th IEEE International Conference on Bioinformatics and Bioengineering, BIBE
Pages1056-1060
Number of pages5
DOIs
Publication statusPublished - 2007
Event7th IEEE International Conference on Bioinformatics and Bioengineering, BIBE - Boston, MA, United States
Duration: Jan 14 2007Jan 17 2007

Other

Other7th IEEE International Conference on Bioinformatics and Bioengineering, BIBE
CountryUnited States
CityBoston, MA
Period1/14/071/17/07

ASJC Scopus subject areas

  • Biotechnology
  • Genetics
  • Bioengineering

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