Abstract
The study demonstrates the ability of an information-theoretic measure, such as the transfer entropy (TE), in detecting the depression of the cardiac baroreflex control and circulatory-cardio mechanical feedforward link during propofol-induced general anesthesia. TE was computed from spontaneous variability of heart period (HP) and systolic arterial pressure (SAP) in patients undergoing coronary artery bypass graft (CABG). TE from SAP to HP and from HP to SAP were evaluated by accounting for the confounding effect of respiration (R) affecting both HP and SAP (i.e. TESAP→HP-R and TEHP→SAP-R respectively). Both TESAP→HP-R and TEHP→SAP-R decreased during general anesthesia, thus suggesting that the strength of the causal relation diminished over both arms of the closed loop HP-SAP control. The squared coherence function between HP and SAP confirmed the decreased HP-SAP coupling during general anesthesia, even though it could not distinguish directionality.
Original language | English |
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Title of host publication | Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS |
Publisher | Institute of Electrical and Electronics Engineers Inc. |
Pages | 4029-4032 |
Number of pages | 4 |
Volume | 2015-November |
ISBN (Print) | 9781424492718 |
DOIs | |
Publication status | Published - Nov 4 2015 |
Event | 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy Duration: Aug 25 2015 → Aug 29 2015 |
Other
Other | 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 |
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Country | Italy |
City | Milan |
Period | 8/25/15 → 8/29/15 |
ASJC Scopus subject areas
- Computer Vision and Pattern Recognition
- Signal Processing
- Biomedical Engineering
- Health Informatics