General anesthesia reduces the information exchange between heart and circulation

Alberto Porta; Vlasta Bari; Andrea Marchi; Beatrice De Maria; Valeria Pistuddi; Marco Ranucci

doi:10.1109/EMBC.2015.7319278

General anesthesia reduces the information exchange between heart and circulation

Alberto Porta, Vlasta Bari, Andrea Marchi, Beatrice De Maria, Valeria Pistuddi, Marco Ranucci

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The study demonstrates the ability of an information-theoretic measure, such as the transfer entropy (TE), in detecting the depression of the cardiac baroreflex control and circulatory-cardio mechanical feedforward link during propofol-induced general anesthesia. TE was computed from spontaneous variability of heart period (HP) and systolic arterial pressure (SAP) in patients undergoing coronary artery bypass graft (CABG). TE from SAP to HP and from HP to SAP were evaluated by accounting for the confounding effect of respiration (R) affecting both HP and SAP (i.e. TE_SAP→HP-R and TE_HP→SAP-R respectively). Both TE_SAP→HP-R and TE_HP→SAP-R decreased during general anesthesia, thus suggesting that the strength of the causal relation diminished over both arms of the closed loop HP-SAP control. The squared coherence function between HP and SAP confirmed the decreased HP-SAP coupling during general anesthesia, even though it could not distinguish directionality.

Original language	English
Title of host publication	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	4029-4032
Number of pages	4
Volume	2015-November
ISBN (Print)	9781424492718
DOIs	https://doi.org/10.1109/EMBC.2015.7319278
Publication status	Published - Nov 4 2015
Event	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy Duration: Aug 25 2015 → Aug 29 2015

Other

Other	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Country/Territory	Italy
City	Milan
Period	8/25/15 → 8/29/15

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Signal Processing
Biomedical Engineering
Health Informatics

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10.1109/EMBC.2015.7319278

Cite this

Porta, A., Bari, V., Marchi, A., De Maria, B., Pistuddi, V., & Ranucci, M. (2015). General anesthesia reduces the information exchange between heart and circulation. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (Vol. 2015-November, pp. 4029-4032). [7319278] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7319278

General anesthesia reduces the information exchange between heart and circulation. / Porta, Alberto ; Bari, Vlasta; Marchi, Andrea; De Maria, Beatrice ; Pistuddi, Valeria ; Ranucci, Marco.

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. p. 4029-4032 7319278.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Porta, A , Bari, V, Marchi, A, De Maria, B , Pistuddi, V & Ranucci, M 2015, General anesthesia reduces the information exchange between heart and circulation. in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. vol. 2015-November, 7319278, Institute of Electrical and Electronics Engineers Inc., pp. 4029-4032, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 8/25/15. https://doi.org/10.1109/EMBC.2015.7319278

Porta A , Bari V, Marchi A, De Maria B , Pistuddi V , Ranucci M. General anesthesia reduces the information exchange between heart and circulation. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November. Institute of Electrical and Electronics Engineers Inc. 2015. p. 4029-4032. 7319278 https://doi.org/10.1109/EMBC.2015.7319278

Porta, Alberto ; Bari, Vlasta ; Marchi, Andrea ; De Maria, Beatrice ; Pistuddi, Valeria ; Ranucci, Marco. / General anesthesia reduces the information exchange between heart and circulation. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. pp. 4029-4032

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abstract = "The study demonstrates the ability of an information-theoretic measure, such as the transfer entropy (TE), in detecting the depression of the cardiac baroreflex control and circulatory-cardio mechanical feedforward link during propofol-induced general anesthesia. TE was computed from spontaneous variability of heart period (HP) and systolic arterial pressure (SAP) in patients undergoing coronary artery bypass graft (CABG). TE from SAP to HP and from HP to SAP were evaluated by accounting for the confounding effect of respiration (R) affecting both HP and SAP (i.e. TESAP→HP-R and TEHP→SAP-R respectively). Both TESAP→HP-R and TEHP→SAP-R decreased during general anesthesia, thus suggesting that the strength of the causal relation diminished over both arms of the closed loop HP-SAP control. The squared coherence function between HP and SAP confirmed the decreased HP-SAP coupling during general anesthesia, even though it could not distinguish directionality.",

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AB - The study demonstrates the ability of an information-theoretic measure, such as the transfer entropy (TE), in detecting the depression of the cardiac baroreflex control and circulatory-cardio mechanical feedforward link during propofol-induced general anesthesia. TE was computed from spontaneous variability of heart period (HP) and systolic arterial pressure (SAP) in patients undergoing coronary artery bypass graft (CABG). TE from SAP to HP and from HP to SAP were evaluated by accounting for the confounding effect of respiration (R) affecting both HP and SAP (i.e. TESAP→HP-R and TEHP→SAP-R respectively). Both TESAP→HP-R and TEHP→SAP-R decreased during general anesthesia, thus suggesting that the strength of the causal relation diminished over both arms of the closed loop HP-SAP control. The squared coherence function between HP and SAP confirmed the decreased HP-SAP coupling during general anesthesia, even though it could not distinguish directionality.

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General anesthesia reduces the information exchange between heart and circulation

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