General paresis: Neuropsychological and SPECT study of five cases

E. Farina, C. Mariani, C. Abbiati, D. Perani, G. Scarlato

Research output: Contribution to journalArticle

Abstract

Although much less common than before the advent of the antibiotics, cognitive impairment due to general paresis can still be found in clinical practice. Five patients with general paresis underwent longitudinal neuropsychological assessment; on the occasion of the final evaluation, Single Photon Emission Tomography (SPECT) was also performed in four cases. The most frequent cognitive deficit at admission was long term spatial memory impairment, which was present in four patients. Only the two patients who received the highest dosage of intravenous penicillin therapy showed significant improvement at neuropsychological tests after treatment. SPECT findings included areas of cortical hypoperfusion and/or perfusion asymmetry in three out of four patients.

Original languageEnglish
Pages (from-to)229-237
Number of pages9
JournalItalian Journal of Neurological Sciences
Volume15
Issue number5
DOIs
Publication statusPublished - May 1994

Fingerprint

Neurosyphilis
Single-Photon Emission-Computed Tomography
Long-Term Memory
Neuropsychological Tests
Photons
Penicillins
Perfusion
Tomography
Anti-Bacterial Agents
Therapeutics

Keywords

  • general paresis
  • neuropsychological tests
  • SPECT

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

General paresis : Neuropsychological and SPECT study of five cases. / Farina, E.; Mariani, C.; Abbiati, C.; Perani, D.; Scarlato, G.

In: Italian Journal of Neurological Sciences, Vol. 15, No. 5, 05.1994, p. 229-237.

Research output: Contribution to journalArticle

Farina, E. ; Mariani, C. ; Abbiati, C. ; Perani, D. ; Scarlato, G. / General paresis : Neuropsychological and SPECT study of five cases. In: Italian Journal of Neurological Sciences. 1994 ; Vol. 15, No. 5. pp. 229-237.
@article{c22ae6720b9a4fb9872a818526e5d141,
title = "General paresis: Neuropsychological and SPECT study of five cases",
abstract = "Although much less common than before the advent of the antibiotics, cognitive impairment due to general paresis can still be found in clinical practice. Five patients with general paresis underwent longitudinal neuropsychological assessment; on the occasion of the final evaluation, Single Photon Emission Tomography (SPECT) was also performed in four cases. The most frequent cognitive deficit at admission was long term spatial memory impairment, which was present in four patients. Only the two patients who received the highest dosage of intravenous penicillin therapy showed significant improvement at neuropsychological tests after treatment. SPECT findings included areas of cortical hypoperfusion and/or perfusion asymmetry in three out of four patients.",
keywords = "general paresis, neuropsychological tests, SPECT",
author = "E. Farina and C. Mariani and C. Abbiati and D. Perani and G. Scarlato",
year = "1994",
month = "5",
doi = "10.1007/BF02342453",
language = "English",
volume = "15",
pages = "229--237",
journal = "Italian Journal of Neurological Sciences",
issn = "0392-0461",
publisher = "Springer Verlag",
number = "5",

}

TY - JOUR

T1 - General paresis

T2 - Neuropsychological and SPECT study of five cases

AU - Farina, E.

AU - Mariani, C.

AU - Abbiati, C.

AU - Perani, D.

AU - Scarlato, G.

PY - 1994/5

Y1 - 1994/5

N2 - Although much less common than before the advent of the antibiotics, cognitive impairment due to general paresis can still be found in clinical practice. Five patients with general paresis underwent longitudinal neuropsychological assessment; on the occasion of the final evaluation, Single Photon Emission Tomography (SPECT) was also performed in four cases. The most frequent cognitive deficit at admission was long term spatial memory impairment, which was present in four patients. Only the two patients who received the highest dosage of intravenous penicillin therapy showed significant improvement at neuropsychological tests after treatment. SPECT findings included areas of cortical hypoperfusion and/or perfusion asymmetry in three out of four patients.

AB - Although much less common than before the advent of the antibiotics, cognitive impairment due to general paresis can still be found in clinical practice. Five patients with general paresis underwent longitudinal neuropsychological assessment; on the occasion of the final evaluation, Single Photon Emission Tomography (SPECT) was also performed in four cases. The most frequent cognitive deficit at admission was long term spatial memory impairment, which was present in four patients. Only the two patients who received the highest dosage of intravenous penicillin therapy showed significant improvement at neuropsychological tests after treatment. SPECT findings included areas of cortical hypoperfusion and/or perfusion asymmetry in three out of four patients.

KW - general paresis

KW - neuropsychological tests

KW - SPECT

UR - http://www.scopus.com/inward/record.url?scp=0028452642&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028452642&partnerID=8YFLogxK

U2 - 10.1007/BF02342453

DO - 10.1007/BF02342453

M3 - Article

C2 - 7960677

AN - SCOPUS:0028452642

VL - 15

SP - 229

EP - 237

JO - Italian Journal of Neurological Sciences

JF - Italian Journal of Neurological Sciences

SN - 0392-0461

IS - 5

ER -