Generalization of the effects of phonological training for anomia using structural equation modelling: A multiple single-case study

P. Vitali, M. Tettamanti, J. Abutalebi, A. I. Ansaldo, D. Perani, S. F. Cappa, Y. Joanette

Research output: Contribution to journalArticlepeer-review

Abstract

Structural Equation Modelling analysis of three longitudinal er-fMRI sessions was used to test the impact of phonological training and of the generalization process on the pattern of brain connectivity during overt picture naming in two chronic anomic patients. Phonological training yielded a positive effect on the trained material. Six months after the training, a generalization of the positive impact on the untrained items was also observed. Connectivity analysis showed that training and generalization effects shared paralleled cortical patterns of functional integration. These findings may represent the neurophysiological correlate of the training-induced cognitive strategies for the compensation of anomia.

Original languageEnglish
Pages (from-to)93-105
Number of pages13
JournalNeurocase
Volume16
Issue number2
DOIs
Publication statusPublished - Apr 2010

Keywords

  • Aphasia recovery
  • Effective connectivity
  • fMRI
  • Generalization
  • Phonological training

ASJC Scopus subject areas

  • Clinical Neurology

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