Generalized juvenile polyposis with mixed pattern and gastric cancer

Romano Sassatelli, Giorgio Bertoni, Luigi Serra, Giuliano Bedogni, Maurizio Ponz De Leon

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Generalized gastrointestinal juvenile polyposis is a rare form of diffuse polyposis in which cancer infrequently develops. A clinical case is described in which gastric polyps showed a variety of histological features, including both in situ and invasive adenocarcinoma. Many mixed lesions were observed, confirming a morphological sequence already documented in colorectal tumorigenesis but still undefined in gastric tumors. The patient seems strongly predisposed to gastric cancer, presumably on a genetic basis, because he developed a malignancy in a hyperplastic juvenile polyp, usually not considered a precancerous lesion. There is no doubt that cases like this may be important for accurate genetic evaluation and biological characterization.

Original languageEnglish
Pages (from-to)910-915
Number of pages6
JournalGastroenterology
Volume104
Issue number3
Publication statusPublished - 1993

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Stomach Neoplasms
Polyps
Stomach
Neoplasms
Carcinogenesis
Adenocarcinoma in Situ

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Sassatelli, R., Bertoni, G., Serra, L., Bedogni, G., & De Leon, M. P. (1993). Generalized juvenile polyposis with mixed pattern and gastric cancer. Gastroenterology, 104(3), 910-915.

Generalized juvenile polyposis with mixed pattern and gastric cancer. / Sassatelli, Romano; Bertoni, Giorgio; Serra, Luigi; Bedogni, Giuliano; De Leon, Maurizio Ponz.

In: Gastroenterology, Vol. 104, No. 3, 1993, p. 910-915.

Research output: Contribution to journalArticle

Sassatelli, R, Bertoni, G, Serra, L, Bedogni, G & De Leon, MP 1993, 'Generalized juvenile polyposis with mixed pattern and gastric cancer', Gastroenterology, vol. 104, no. 3, pp. 910-915.
Sassatelli R, Bertoni G, Serra L, Bedogni G, De Leon MP. Generalized juvenile polyposis with mixed pattern and gastric cancer. Gastroenterology. 1993;104(3):910-915.
Sassatelli, Romano ; Bertoni, Giorgio ; Serra, Luigi ; Bedogni, Giuliano ; De Leon, Maurizio Ponz. / Generalized juvenile polyposis with mixed pattern and gastric cancer. In: Gastroenterology. 1993 ; Vol. 104, No. 3. pp. 910-915.
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