Abstract
Generalized gastrointestinal juvenile polyposis is a rare form of diffuse polyposis in which cancer infrequently develops. A clinical case is described in which gastric polyps showed a variety of histological features, including both in situ and invasive adenocarcinoma. Many mixed lesions were observed, confirming a morphological sequence already documented in colorectal tumorigenesis but still undefined in gastric tumors. The patient seems strongly predisposed to gastric cancer, presumably on a genetic basis, because he developed a malignancy in a hyperplastic juvenile polyp, usually not considered a precancerous lesion. There is no doubt that cases like this may be important for accurate genetic evaluation and biological characterization.
| Original language | English |
|---|---|
| Pages (from-to) | 910-915 |
| Number of pages | 6 |
| Journal | Gastroenterology |
| Volume | 104 |
| Issue number | 3 |
| Publication status | Published - 1993 |
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ASJC Scopus subject areas
- Gastroenterology
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Generalized juvenile polyposis with mixed pattern and gastric cancer. / Sassatelli, Romano; Bertoni, Giorgio; Serra, Luigi; Bedogni, Giuliano; De Leon, Maurizio Ponz.
In: Gastroenterology, Vol. 104, No. 3, 1993, p. 910-915.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Generalized juvenile polyposis with mixed pattern and gastric cancer
AU - Sassatelli, Romano
AU - Bertoni, Giorgio
AU - Serra, Luigi
AU - Bedogni, Giuliano
AU - De Leon, Maurizio Ponz
PY - 1993
Y1 - 1993
N2 - Generalized gastrointestinal juvenile polyposis is a rare form of diffuse polyposis in which cancer infrequently develops. A clinical case is described in which gastric polyps showed a variety of histological features, including both in situ and invasive adenocarcinoma. Many mixed lesions were observed, confirming a morphological sequence already documented in colorectal tumorigenesis but still undefined in gastric tumors. The patient seems strongly predisposed to gastric cancer, presumably on a genetic basis, because he developed a malignancy in a hyperplastic juvenile polyp, usually not considered a precancerous lesion. There is no doubt that cases like this may be important for accurate genetic evaluation and biological characterization.
AB - Generalized gastrointestinal juvenile polyposis is a rare form of diffuse polyposis in which cancer infrequently develops. A clinical case is described in which gastric polyps showed a variety of histological features, including both in situ and invasive adenocarcinoma. Many mixed lesions were observed, confirming a morphological sequence already documented in colorectal tumorigenesis but still undefined in gastric tumors. The patient seems strongly predisposed to gastric cancer, presumably on a genetic basis, because he developed a malignancy in a hyperplastic juvenile polyp, usually not considered a precancerous lesion. There is no doubt that cases like this may be important for accurate genetic evaluation and biological characterization.
UR - http://www.scopus.com/inward/record.url?scp=0027502124&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027502124&partnerID=8YFLogxK
M3 - Article
C2 - 8440442
AN - SCOPUS:0027502124
VL - 104
SP - 910
EP - 915
JO - Gastroenterology
JF - Gastroenterology
SN - 0016-5085
IS - 3
ER -