Abstract
The case reported, known as lipid storage myopathy, occurred in a 20 year old woman. The first symptoms between the age of 14 and 16 yr. A complete autopsy was carried out. The entire musculature was involved. There was fatty infiltration of the myocardium as well as marked fatty degeneration of the liver and kidneys. Histological and histochemical examination revealed an accumulation of triglycerides, distributed throughout almost all the organs, this being confirmed by chemical examinations. The latter did not, however, show any changes in phospho glyco sulpho lipid, cholesterol or cholesterol content. Gas chromatography of the total free fatty acids revealed an increase in short chain fatty acids. The authors stress the generalized nature of the pathological process leading to the accumulation of triglycerides, in a disease which up to present time had been considered to be a myopathy, and therefore propose the name generalised triglyceridosis of generalised triglyceride lipidosis.
| Original language | French |
|---|---|
| Pages (from-to) | 629-644 |
| Number of pages | 16 |
| Journal | Revue Neurologique |
| Volume | 131 |
| Issue number | 9 |
| Publication status | Published - 1975 |
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ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)
Cite this
LIPIDOSE GENERALISEE A TRIGLYCERIDES (TRIGLYCERIDOSE). PREMIERE CONTRIBUTION ANATOMO CLINIQUE. / Cornelio, F.; Allegranza, A.; Bizzi, A.
In: Revue Neurologique, Vol. 131, No. 9, 1975, p. 629-644.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - LIPIDOSE GENERALISEE A TRIGLYCERIDES (TRIGLYCERIDOSE). PREMIERE CONTRIBUTION ANATOMO CLINIQUE
AU - Cornelio, F.
AU - Allegranza, A.
AU - Bizzi, A.
PY - 1975
Y1 - 1975
N2 - The case reported, known as lipid storage myopathy, occurred in a 20 year old woman. The first symptoms between the age of 14 and 16 yr. A complete autopsy was carried out. The entire musculature was involved. There was fatty infiltration of the myocardium as well as marked fatty degeneration of the liver and kidneys. Histological and histochemical examination revealed an accumulation of triglycerides, distributed throughout almost all the organs, this being confirmed by chemical examinations. The latter did not, however, show any changes in phospho glyco sulpho lipid, cholesterol or cholesterol content. Gas chromatography of the total free fatty acids revealed an increase in short chain fatty acids. The authors stress the generalized nature of the pathological process leading to the accumulation of triglycerides, in a disease which up to present time had been considered to be a myopathy, and therefore propose the name generalised triglyceridosis of generalised triglyceride lipidosis.
AB - The case reported, known as lipid storage myopathy, occurred in a 20 year old woman. The first symptoms between the age of 14 and 16 yr. A complete autopsy was carried out. The entire musculature was involved. There was fatty infiltration of the myocardium as well as marked fatty degeneration of the liver and kidneys. Histological and histochemical examination revealed an accumulation of triglycerides, distributed throughout almost all the organs, this being confirmed by chemical examinations. The latter did not, however, show any changes in phospho glyco sulpho lipid, cholesterol or cholesterol content. Gas chromatography of the total free fatty acids revealed an increase in short chain fatty acids. The authors stress the generalized nature of the pathological process leading to the accumulation of triglycerides, in a disease which up to present time had been considered to be a myopathy, and therefore propose the name generalised triglyceridosis of generalised triglyceride lipidosis.
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UR - http://www.scopus.com/inward/citedby.url?scp=0016719391&partnerID=8YFLogxK
M3 - Articolo
C2 - 1224117
AN - SCOPUS:0016719391
VL - 131
SP - 629
EP - 644
JO - Revue Neurologique
JF - Revue Neurologique
SN - 0035-3787
IS - 9
ER -