Generation and characterization of a murine monoclonal antibody specific for the human T1-CD5 molecule.

F. Genzano, A. Funaro, M. Alessio, L. B. De Monte, G. Bellone, L. Peruzzi, M. Zaccolo, F. Caligari-Cappino, F. Malavasi

Research output: Contribution to journalArticlepeer-review

Abstract

Murine monoclonal antibodies (MoAbs) have found widespread applications in the characterization of the molecular and functional features of lymphocyte differentiation antigens. The present paper summarizes the results of our work dealing with the production and selection of a murine MoAb recognizing a molecule expressed during the whole differentiative life of T lymphocytes. The MoAb CB01 resulted to be specific for an apparently unique epitope of the T-cell specific membrane glycoprotein T1-CD5.

Original languageEnglish
Pages (from-to)143-150
Number of pages8
JournalInternational Journal of Biological Markers
Volume2
Issue number3
Publication statusPublished - Sep 1987

ASJC Scopus subject areas

  • Biochemistry
  • Immunology

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