TY - JOUR
T1 - Generation of the human induced pluripotent stem cell (hiPSC) line PSMi004-A from a carrier of the KCNQ1-R594Q mutation
AU - Mura, Manuela
AU - Lee, Yee Ki
AU - Pisano, Federica
AU - Ginevrino, Monia
AU - Boni, Marina
AU - Calabrò, Federica
AU - Crotti, Lia
AU - Valente, Enza Maria
AU - Schwartz, Peter J.
AU - Tse, Hung Fat
AU - Gnecchi, Massimiliano
PY - 2019/5/1
Y1 - 2019/5/1
N2 - We generated human induced pluripotent stem cells (hiPSCs) from dermal fibroblasts of a male carrier of the heterozygous mutation c.1781 G > A p.R594Q on the KCNQ1 gene. hiPSCs, generated using four retroviruses each encoding for OCT4, SOX2, KLF4 and cMYC, display pluripotent stem cell characteristics, and can be differentiated into spontaneously beating cardiomyocytes (hiPSC-CMs).
AB - We generated human induced pluripotent stem cells (hiPSCs) from dermal fibroblasts of a male carrier of the heterozygous mutation c.1781 G > A p.R594Q on the KCNQ1 gene. hiPSCs, generated using four retroviruses each encoding for OCT4, SOX2, KLF4 and cMYC, display pluripotent stem cell characteristics, and can be differentiated into spontaneously beating cardiomyocytes (hiPSC-CMs).
UR - http://www.scopus.com/inward/record.url?scp=85063950564&partnerID=8YFLogxK
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U2 - 10.1016/j.scr.2019.101431
DO - 10.1016/j.scr.2019.101431
M3 - Article
AN - SCOPUS:85063950564
VL - 37
JO - Stem Cell Research
JF - Stem Cell Research
SN - 1873-5061
M1 - 101431
ER -