Genetic differences in daily rhythms of pain sensivity in mice

Claudio Castellano; Stefano Puglisi-Allegra; Paolo Renzi; Alberto Oliverio

doi:10.1016/0091-3057(85)90135-2

Genetic differences in daily rhythms of pain sensivity in mice

Claudio Castellano, Stefano Puglisi-Allegra, Paolo Renzi, Alberto Oliverio

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

A dark phase increase in pain sensitivity was evident in C57BL/6 inbred mice. On the contrary, Swiss mice are characterized by decreased nocturnal pain sensitivity. The latter finding is in agreement with a number of previous studies based on albino mice. However, our findings indicate that (1) nocturnal decreased pain sensitivity is not the rule in the mouse and (2) large differences are evident when the onset in peak nocturnal analgesia is considered.

Original language	English
Pages (from-to)	91-92
Number of pages	2
Journal	Pharmacology, Biochemistry and Behavior
Volume	23
Issue number	1
DOIs	https://doi.org/10.1016/0091-3057(85)90135-2
Publication status	Published - 1985

Keywords

Analgesia
Circadian rhythms
Mice
Opioid peptides
Stress

ASJC Scopus subject areas

Biochemistry
Behavioral Neuroscience
Pharmacology

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AU - Castellano, Claudio

AU - Puglisi-Allegra, Stefano

AU - Renzi, Paolo

AU - Oliverio, Alberto

PY - 1985

Y1 - 1985

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AB - A dark phase increase in pain sensitivity was evident in C57BL/6 inbred mice. On the contrary, Swiss mice are characterized by decreased nocturnal pain sensitivity. The latter finding is in agreement with a number of previous studies based on albino mice. However, our findings indicate that (1) nocturnal decreased pain sensitivity is not the rule in the mouse and (2) large differences are evident when the onset in peak nocturnal analgesia is considered.

KW - Analgesia

KW - Circadian rhythms

KW - Mice

KW - Opioid peptides

KW - Stress

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Genetic differences in daily rhythms of pain sensivity in mice

Abstract

Keywords

ASJC Scopus subject areas

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