Genetic diversity of invasive strains of Haemophilus influenzae type b before and after introduction of the conjugate vaccine in Italy

Marina Cerquetti; Rita Cardines; Maria Giufrè; Tonino Sofia; Fabio D'Ambrosio; Paola Mastrantonio; Marta Luisa Ciofi Degli Atti

doi:10.1086/505499

Genetic diversity of invasive strains of Haemophilus influenzae type b before and after introduction of the conjugate vaccine in Italy

Marina Cerquetti, Rita Cardines, Maria Giufrè, Tonino Sofia, Fabio D'Ambrosio, Paola Mastrantonio, Marta Luisa Ciofi Degli Atti

Ospedale Pediatrico Bambino Gesu

Research output: Contribution to journal › Article › peer-review

Abstract

We determined the genotypes of 95 invasive Haemophilus influenzae type b (Hib) strains collected before and after introduction of widespread Hib vaccination in Italy. No substantial change in genetic diversity was highlighted by pulsed-field gel electrophoresis, However, an upward temporal trend in proportion of strains possessing multiple copies of the capsulation b locus was detected (P = .03).

Original language	English
Pages (from-to)	317-319
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	43
Issue number	3
DOIs	https://doi.org/10.1086/505499
Publication status	Published - Aug 1 2006

ASJC Scopus subject areas

Immunology

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AU - Cerquetti, Marina

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AU - Giufrè, Maria

AU - Sofia, Tonino

AU - D'Ambrosio, Fabio

AU - Mastrantonio, Paola

AU - Ciofi Degli Atti, Marta Luisa

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Genetic diversity of invasive strains of Haemophilus influenzae type b before and after introduction of the conjugate vaccine in Italy

Abstract

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