Genetic diversity of invasive strains of Haemophilus influenzae type b before and after introduction of the conjugate vaccine in Italy

Marina Cerquetti, Rita Cardines, Maria Giufrè, Tonino Sofia, Fabio D'Ambrosio, Paola Mastrantonio, Marta Luisa Ciofi Degli Atti

Research output: Contribution to journalArticlepeer-review

Abstract

We determined the genotypes of 95 invasive Haemophilus influenzae type b (Hib) strains collected before and after introduction of widespread Hib vaccination in Italy. No substantial change in genetic diversity was highlighted by pulsed-field gel electrophoresis, However, an upward temporal trend in proportion of strains possessing multiple copies of the capsulation b locus was detected (P = .03).

Original languageEnglish
Pages (from-to)317-319
Number of pages3
JournalClinical Infectious Diseases
Volume43
Issue number3
DOIs
Publication statusPublished - Aug 1 2006

ASJC Scopus subject areas

  • Immunology

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