TY - JOUR
T1 - Genetic heterogeneity among the Hindus and their relationships with the other 'Caucasoid' populations
T2 - New data on Punjab-Haryana and Rajasthan Indian States
AU - Tartaglia, M.
AU - Scacchi, R.
AU - Corbo, R. M.
AU - Pompei, F.
AU - Rickards, O.
AU - Ciminelli, B. M.
AU - Sangatramani, T.
AU - Vyas, M.
AU - Dash, S.
AU - Modiano, G.
PY - 1995
Y1 - 1995
N2 - The genetic structure of Rajasthan Hindus and Punjab-Haryana Hindus and Sikhs has been studied for ABO RH, APOC2, C6, C7, F13A, F13B, HP, ORM1, ACP1, ADA, AK1, ESD, GLO1, PGD, PGM1 subtyping, and PGP. This is the first genetic survey on Hindus of Rajasthan. Furthermore, many of these markers have never been studied on Hindus before (APOC2, C6, C7, F13A, F13B, ORM1, PGP). These data, together with those previously available for Hindus, have been utilized to analyze the within-Hindus genetic heterogeneity by R(ST) statistic and correspondence analysis. The genetic relationships of Hindus to other Causcasoid populations were also investigated. In the first analysis, two eastern states (Orissa and Andhra Pradesh) were found to be quite separate from each other and clearly distinct from the northwestern and western states. Out of the markers which could not be utilized in this analysis, PGM1 subtyping turned out to discriminate between the Dravidian-speaking and the Indo-Aryan-speaking Hindus. The second analysis shows a clear-cut separation of Hindus from Europeans, with Near Eastern and Middle Eastern populations genetically in an intermediate position.
AB - The genetic structure of Rajasthan Hindus and Punjab-Haryana Hindus and Sikhs has been studied for ABO RH, APOC2, C6, C7, F13A, F13B, HP, ORM1, ACP1, ADA, AK1, ESD, GLO1, PGD, PGM1 subtyping, and PGP. This is the first genetic survey on Hindus of Rajasthan. Furthermore, many of these markers have never been studied on Hindus before (APOC2, C6, C7, F13A, F13B, ORM1, PGP). These data, together with those previously available for Hindus, have been utilized to analyze the within-Hindus genetic heterogeneity by R(ST) statistic and correspondence analysis. The genetic relationships of Hindus to other Causcasoid populations were also investigated. In the first analysis, two eastern states (Orissa and Andhra Pradesh) were found to be quite separate from each other and clearly distinct from the northwestern and western states. Out of the markers which could not be utilized in this analysis, PGM1 subtyping turned out to discriminate between the Dravidian-speaking and the Indo-Aryan-speaking Hindus. The second analysis shows a clear-cut separation of Hindus from Europeans, with Near Eastern and Middle Eastern populations genetically in an intermediate position.
KW - Hindus
KW - Population genetics
KW - Serum and erythrocyte markers
UR - http://www.scopus.com/inward/record.url?scp=0028863601&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028863601&partnerID=8YFLogxK
U2 - 10.1002/ajpa.1330980303
DO - 10.1002/ajpa.1330980303
M3 - Article
C2 - 8572153
AN - SCOPUS:0028863601
VL - 98
SP - 257
EP - 273
JO - American Journal of Physical Anthropology
JF - American Journal of Physical Anthropology
SN - 0002-9483
IS - 3
ER -