| Original language | English |
|---|---|
| Pages (from-to) | 414-430 |
| Number of pages | 17 |
| Journal | Nature Genetics |
| Volume | 51 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2019 |
Keywords
- amyloid beta protein
- lipid
- tau protein
- aged
- Alzheimer disease
- case control study
- female
- gene locus
- genetic predisposition
- genetic screening
- genetics
- genome-wide association study
- haplotype
- human
- immunity
- lipid metabolism
- male
- meta analysis
- procedures
- Aged
- Alzheimer Disease
- Amyloid beta-Peptides
- Case-Control Studies
- Female
- Genetic Loci
- Genetic Predisposition to Disease
- Genetic Testing
- Genome-Wide Association Study
- Haplotypes
- Humans
- Immunity
- Lipid Metabolism
- Lipids
- Male
- tau Proteins
Cite this
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. / Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s DiseaseInitiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES).
In: Nature Genetics, Vol. 51, No. 3, 2019, p. 414-430.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
AU - Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s DiseaseInitiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environ
AU - Kunkle, B.W.
AU - Grenier-Boley, B.
AU - Sims, R.
AU - Bis, J.C.
AU - Damotte, V.
AU - Naj, A.C.
AU - Boland, A.
AU - Vronskaya, M.
AU - van der Lee, S.J.
AU - Amlie-Wolf, A.
AU - Bellenguez, C.
AU - Frizatti, A.
AU - Chouraki, V.
AU - Martin, E.R.
AU - Sleegers, K.
AU - Badarinarayan, N.
AU - Jakobsdottir, J.
AU - Hamilton-Nelson, K.L.
AU - Moreno-Grau, S.
AU - Olaso, R.
AU - Raybould, R.
AU - Chen, Y.
AU - Kuzma, A.B.
AU - Hiltunen, M.
AU - Morgan, T.
AU - Ahmad, S.
AU - Vardarajan, B.N.
AU - Epelbaum, J.
AU - Hoffmann, P.
AU - Boada, M.
AU - Beecham, G.W.
AU - Hughes, J.T.
AU - Galimberti, D.
AU - Scarpini, E.
AU - Salani, F.
AU - Ciaramella, A.
AU - Mancuso, M.
AU - Russo, G.
AU - Daniele, A.
AU - Sorbi, S.
AU - Sacchinelli, E.
AU - Spalletta, G.
AU - Caltagirone, C.
AU - Bossù, P.
AU - Orfei, M.D.
AU - Gallo, M.
AU - Cuccaro, M.L.
AU - Spina, S.
AU - Pilotto, A.
AU - Bosco, P.
N1 - Export Date: 26 August 2019 CODEN: NGENE Correspondence Address: Kunkle, B.W.; John P. Hussman Institute for Human Genomics, University of Miami Miller School of MedicineUnited States; email: bkunkle@miami.edu
PY - 2019
Y1 - 2019
KW - amyloid beta protein
KW - lipid
KW - tau protein
KW - aged
KW - Alzheimer disease
KW - case control study
KW - female
KW - gene locus
KW - genetic predisposition
KW - genetic screening
KW - genetics
KW - genome-wide association study
KW - haplotype
KW - human
KW - immunity
KW - lipid metabolism
KW - male
KW - meta analysis
KW - procedures
KW - Aged
KW - Alzheimer Disease
KW - Amyloid beta-Peptides
KW - Case-Control Studies
KW - Female
KW - Genetic Loci
KW - Genetic Predisposition to Disease
KW - Genetic Testing
KW - Genome-Wide Association Study
KW - Haplotypes
KW - Humans
KW - Immunity
KW - Lipid Metabolism
KW - Lipids
KW - Male
KW - tau Proteins
U2 - 10.1038/s41588-019-0358-2
DO - 10.1038/s41588-019-0358-2
M3 - Article
VL - 51
SP - 414
EP - 430
JO - Nature Genetics
JF - Nature Genetics
SN - 1061-4036
IS - 3
ER -