Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s DiseaseInitiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES)

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)414-430
Number of pages17
JournalNature Genetics
Volume51
Issue number3
DOIs
Publication statusPublished - 2019

Keywords

  • amyloid beta protein
  • lipid
  • tau protein
  • aged
  • Alzheimer disease
  • case control study
  • female
  • gene locus
  • genetic predisposition
  • genetic screening
  • genetics
  • genome-wide association study
  • haplotype
  • human
  • immunity
  • lipid metabolism
  • male
  • meta analysis
  • procedures
  • Aged
  • Alzheimer Disease
  • Amyloid beta-Peptides
  • Case-Control Studies
  • Female
  • Genetic Loci
  • Genetic Predisposition to Disease
  • Genetic Testing
  • Genome-Wide Association Study
  • Haplotypes
  • Humans
  • Immunity
  • Lipid Metabolism
  • Lipids
  • Male
  • tau Proteins

Cite this