De la génétique des adénomes hypophysaires familiaux

Translated title of the contribution: Genetics of familial pituitary adenomas

Albert Beckers, Marie Lise Jaffrain-Rea, Adrian F. Daly

Research output: Contribution to journalArticlepeer-review


Pituitary adenomas were previously thought to be rare. However, a recent cross-sectional study conducted in Liège, Belgium, showed that clinically apparent pituitary adenomas were present in about 1 in 1000 inhabitants, which is 4 to 5 times the previously reported prevalence. Pituitary adenomas are generally sporadic, but some are associated with familial-isolated tumoral syndromes (mainly MENl and Carney complex). With the recent characterization of FIPA ( Familial Isolated Pituitary Adenomas), familial pituitary adenomas are now thought to account for 5% to 8% of all pituitary tumors. New genetic mechanisms are being identified, improving our understanding of the complex manifestations and sometimes unpredictable outcome of pituitary adenomas.

Translated title of the contributionGenetics of familial pituitary adenomas
Original languageFrench
Pages (from-to)1557-1571
Number of pages15
JournalBulletin de l'Academie Nationale de Medecine
Issue number7
Publication statusPublished - Oct 2009


  • Genetics
  • Multiple endocrine neoplasia type I. aryl hydrocarbon receptor-interacting PROTEIN [substance name
  • Pituitary neoplasms/

ASJC Scopus subject areas

  • Medicine(all)


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