Pituitary adenomas were previously thought to be rare. However, a recent cross-sectional study conducted in Liège, Belgium, showed that clinically apparent pituitary adenomas were present in about 1 in 1000 inhabitants, which is 4 to 5 times the previously reported prevalence. Pituitary adenomas are generally sporadic, but some are associated with familial-isolated tumoral syndromes (mainly MENl and Carney complex). With the recent characterization of FIPA ( Familial Isolated Pituitary Adenomas), familial pituitary adenomas are now thought to account for 5% to 8% of all pituitary tumors. New genetic mechanisms are being identified, improving our understanding of the complex manifestations and sometimes unpredictable outcome of pituitary adenomas.
|Translated title of the contribution||Genetics of familial pituitary adenomas|
|Number of pages||15|
|Journal||Bulletin de l'Academie Nationale de Medecine|
|Publication status||Published - Oct 2009|
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- Pituitary neoplasms/
ASJC Scopus subject areas