Genomics of acute myeloid leukemia: The next generation

Research output: Contribution to journalArticle

Abstract

Acute myeloid leukemia (AML) is, as other types of cancer, a genetic disorder of somatic cells. The detection of somatic molecular abnormalities that may cause and maintain AML is crucial for patient stratification. The development of mutation-specific therapeutic interventions will hopefully increase cure rates and improve patients' quality of life. This review illustrates how next generation sequencing technologies are changing the study of cancer genomics of adult AML patients.

Original languageEnglish
Article numberArticle 40
JournalFrontiers in Oncology
Volume2 MAY
DOIs
Publication statusPublished - 2012

Keywords

  • Acute myeloid leukemia
  • Next generation sequencing
  • Recurrent mutations
  • Somatic mutations

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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