Abstract
The associations between selected biomarkers of biologically effective dose (32P-post-labelling-DNA adducts), early biological effects (Micronuclei, MN) and sister chromatid exchanges (SCE) and individual measurements of exposure to benzo(a)pyrene (a surrogate index of exposure to polynuclear aromatic hydrocarbons, PAHs) are investigated in a study being conducted among traffic police workers and referent subjects in the City of Genova, Italy. Preliminary findings show B(a)P mean values of 1.33 ng/m3, SD = 1.35 ng/m3 and 0.06, SD = 0.17 in traffic police workers and referent subjects, respectively. Micronuclei mean levels in peripheral blood lymphocytes of 26 traffic police workers and 25 referents were 3.30, DS = 1.24 e 3.90, DS = 1.50 (per 1,000 binucleated cells). Eleven subjects (61%) out of 18 had detectable levels of DNA adducts (32P-post-labelling technique, range 1.8-9.0 Relative Adduct Level (RAL) per 10(9) nucleotides).
| Original language | Italian |
|---|---|
| Pages (from-to) | 120-123 |
| Number of pages | 4 |
| Journal | Epidemiologia e prevenzione |
| Volume | 19 |
| Issue number | 62 |
| Publication status | Published - Mar 1995 |
Fingerprint
ASJC Scopus subject areas
- Medicine(all)
Cite this
Danno genotossico in esposti ad inquinanti atmosferici da traffico veicolare : risultati preliminari. / Merlo, F.; Bolognesi, C.; Peluso, M.; Valerio, F.; Abbondandolo, A.; Puntoni, R.
In: Epidemiologia e prevenzione, Vol. 19, No. 62, 03.1995, p. 120-123.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Danno genotossico in esposti ad inquinanti atmosferici da traffico veicolare
T2 - risultati preliminari.
AU - Merlo, F.
AU - Bolognesi, C.
AU - Peluso, M.
AU - Valerio, F.
AU - Abbondandolo, A.
AU - Puntoni, R.
PY - 1995/3
Y1 - 1995/3
N2 - The associations between selected biomarkers of biologically effective dose (32P-post-labelling-DNA adducts), early biological effects (Micronuclei, MN) and sister chromatid exchanges (SCE) and individual measurements of exposure to benzo(a)pyrene (a surrogate index of exposure to polynuclear aromatic hydrocarbons, PAHs) are investigated in a study being conducted among traffic police workers and referent subjects in the City of Genova, Italy. Preliminary findings show B(a)P mean values of 1.33 ng/m3, SD = 1.35 ng/m3 and 0.06, SD = 0.17 in traffic police workers and referent subjects, respectively. Micronuclei mean levels in peripheral blood lymphocytes of 26 traffic police workers and 25 referents were 3.30, DS = 1.24 e 3.90, DS = 1.50 (per 1,000 binucleated cells). Eleven subjects (61%) out of 18 had detectable levels of DNA adducts (32P-post-labelling technique, range 1.8-9.0 Relative Adduct Level (RAL) per 10(9) nucleotides).
AB - The associations between selected biomarkers of biologically effective dose (32P-post-labelling-DNA adducts), early biological effects (Micronuclei, MN) and sister chromatid exchanges (SCE) and individual measurements of exposure to benzo(a)pyrene (a surrogate index of exposure to polynuclear aromatic hydrocarbons, PAHs) are investigated in a study being conducted among traffic police workers and referent subjects in the City of Genova, Italy. Preliminary findings show B(a)P mean values of 1.33 ng/m3, SD = 1.35 ng/m3 and 0.06, SD = 0.17 in traffic police workers and referent subjects, respectively. Micronuclei mean levels in peripheral blood lymphocytes of 26 traffic police workers and 25 referents were 3.30, DS = 1.24 e 3.90, DS = 1.50 (per 1,000 binucleated cells). Eleven subjects (61%) out of 18 had detectable levels of DNA adducts (32P-post-labelling technique, range 1.8-9.0 Relative Adduct Level (RAL) per 10(9) nucleotides).
UR - http://www.scopus.com/inward/record.url?scp=0029268940&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029268940&partnerID=8YFLogxK
M3 - Articolo
C2 - 7541363
AN - SCOPUS:0029268940
VL - 19
SP - 120
EP - 123
JO - Epidemiologia e prevenzione
JF - Epidemiologia e prevenzione
SN - 1120-9763
IS - 62
ER -