Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance

Research output: Contribution to journalArticle

Abstract

DNA fragments released from cancer cells into the blood can be used to generate molecular profiles of tumors. Non-invasive 'liquid biopsies' can be used to monitor minimal residual disease and detect the emergence of drug resistance.

Original languageEnglish
JournalGenome Biology
DOIs
Publication statusAccepted/In press - Aug 30 2014

Fingerprint

drug resistance
Disease Resistance
disease resistance
Drug Resistance
tumor
genotyping
biopsy
cancer
blood
DNA
liquid
neoplasms
liquids
Residual Neoplasm
Blood Cells
Neoplasms
cells
Biopsy
neoplasm cells

ASJC Scopus subject areas

  • Cell Biology
  • Ecology, Evolution, Behavior and Systematics
  • Genetics

Cite this

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abstract = "DNA fragments released from cancer cells into the blood can be used to generate molecular profiles of tumors. Non-invasive 'liquid biopsies' can be used to monitor minimal residual disease and detect the emergence of drug resistance.",
author = "Giulia Siravegna and Alberto Bardelli",
year = "2014",
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language = "English",
journal = "Genome Biology",
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