Gestational diabetes mellitus: Including serum pregnancy-associated plasma protein-A testing in the clinical management of primiparous women? A case-control study

Elisabetta Lovati, Fausta Beneventi, Margherita Simonetta, Marco Laneri, Lara Quarleri, Luigia Scudeller, Giulia Albonico, Elena Locatelli, Chiara Cavagnoli, Carmine Tinelli, Arsenio Spinillo, Gino R. Corazza

Research output: Contribution to journalArticle

Abstract

Aims: To assess pregnancy-associated plasma protein A (PAPP-A) correlation with GDM and its usefulness in predicting GDM in primiparous women. Methods: First trimester data related to 307 pregnant women affected by GDM and 366 control pregnant women were retrieved from a computer data base and integrated with ad hoc data. Clinical data were recorded at delivery. A logistic model was used to analyze the association between first trimester data and subsequent clinical outcomes. We derived a risk score using both classical risk factors for GDM and PAPP-A. Results: Diabetic and control women were significantly different in terms of age (p

Original languageEnglish
Pages (from-to)340-347
Number of pages8
JournalDiabetes Research and Clinical Practice
Volume100
Issue number3
DOIs
Publication statusPublished - Jun 2013

Keywords

  • Clinical risk score
  • First trimester screening
  • Gestational diabetes mellitus
  • PAPP-A
  • Primiparous

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine
  • Endocrinology

Fingerprint Dive into the research topics of 'Gestational diabetes mellitus: Including serum pregnancy-associated plasma protein-A testing in the clinical management of primiparous women? A case-control study'. Together they form a unique fingerprint.

  • Cite this