GH release after GHRH plus arginine administration in obese and overweight women with polycystic ovary syndrome

F. Orio, S. Palomba, A. Colao, T. Russo, C. Dentico, L. Tauchmanovà, S. Savastano, C. Nappi, C. Sultan, F. Zullo, G. Lombardi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Few and unclear data are available in the literature about the relationship between impairment of GH/IGFJ axis and polycystic ovary syndrome (PCOS). This study was aimed to evaluate the basal GH and IGF- levels, and GH release after challenge test in obese and overweight women with PCOS. Thirty patients with PCOS and other 30 healthy women matched for age, body mass index (BMI) and waist-hip ratio (WHR) were studied. Serum follicle-stimulating hormone (FSH), LH, PRL, E2, P, 17OH-progesterone (17OH-P), total T, δ4, DHEA-S, SHBG, GH and IGF-I levels were evaluated in each subject. A GHRH plus arginine challenge test was performed in all subjects. After provocative test, in PCOS and control women the GH levels were significantly (p

Original languageEnglish
Pages (from-to)117-122
Number of pages6
JournalJournal of Endocrinological Investigation
Volume26
Issue number2
Publication statusPublished - Feb 2003

Fingerprint

Polycystic Ovary Syndrome
Arginine
Waist-Hip Ratio
Dehydroepiandrosterone
Follicle Stimulating Hormone
Insulin-Like Growth Factor I
Progesterone
Body Mass Index
Serum

Keywords

  • Arginine
  • BMI
  • GH
  • GHRH
  • IGF-I
  • Obesity
  • PCOS

ASJC Scopus subject areas

  • Endocrinology

Cite this

Orio, F., Palomba, S., Colao, A., Russo, T., Dentico, C., Tauchmanovà, L., ... Lombardi, G. (2003). GH release after GHRH plus arginine administration in obese and overweight women with polycystic ovary syndrome. Journal of Endocrinological Investigation, 26(2), 117-122.

GH release after GHRH plus arginine administration in obese and overweight women with polycystic ovary syndrome. / Orio, F.; Palomba, S.; Colao, A.; Russo, T.; Dentico, C.; Tauchmanovà, L.; Savastano, S.; Nappi, C.; Sultan, C.; Zullo, F.; Lombardi, G.

In: Journal of Endocrinological Investigation, Vol. 26, No. 2, 02.2003, p. 117-122.

Research output: Contribution to journalArticle

Orio, F, Palomba, S, Colao, A, Russo, T, Dentico, C, Tauchmanovà, L, Savastano, S, Nappi, C, Sultan, C, Zullo, F & Lombardi, G 2003, 'GH release after GHRH plus arginine administration in obese and overweight women with polycystic ovary syndrome', Journal of Endocrinological Investigation, vol. 26, no. 2, pp. 117-122.
Orio, F. ; Palomba, S. ; Colao, A. ; Russo, T. ; Dentico, C. ; Tauchmanovà, L. ; Savastano, S. ; Nappi, C. ; Sultan, C. ; Zullo, F. ; Lombardi, G. / GH release after GHRH plus arginine administration in obese and overweight women with polycystic ovary syndrome. In: Journal of Endocrinological Investigation. 2003 ; Vol. 26, No. 2. pp. 117-122.
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