GH secretion reserve in subclinical hypercortisolism

Serena Palmieri, Valentina Morelli, Antonio Stefano Salcuni, Cristina Eller-Vainicher, Elisa Cairoli, Volha V. Zhukouskaya, Paolo Beck-Peccoz, Alfredo Scillitani, Iacopo Chiodini

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: In overt hypercortisolism, growth hormone (GH) secretion is decreased and normalizes after surgery. In subclinical hypercortisolism (SH), GH secretion has been scarcely investigated. We assessed GH reserve in patients with and without SH and, in the former, also after recovery. Methods: We enrolled 24 patients with adrenal adenomas, 12 with SH (SH+, 8 females, 58.3 ± 6.5 years) and 12 without SH (SH−; 11 females, 61.8 ± 10.6 years). SH was diagnosed in the presence of ≥2 out of: 1 mg overnight dexamethasone suppression test >83 nmol/L, urinary free cortisol (UFC) >193 nmol/day and ACTH levels 

Original languageEnglish
Pages (from-to)470-476
Number of pages7
JournalPituitary
Volume17
Issue number5
DOIs
Publication statusPublished - Oct 1 2014

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Cushing Syndrome
Growth Hormone
Adenoma
Adrenocorticotropic Hormone
Dexamethasone
Hydrocortisone

Keywords

  • Adrenal incidentaloma
  • Adrenalectomy
  • Growth hormone
  • Subclinical hypercortisolism

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Medicine(all)

Cite this

GH secretion reserve in subclinical hypercortisolism. / Palmieri, Serena; Morelli, Valentina; Salcuni, Antonio Stefano; Eller-Vainicher, Cristina; Cairoli, Elisa; Zhukouskaya, Volha V.; Beck-Peccoz, Paolo; Scillitani, Alfredo; Chiodini, Iacopo.

In: Pituitary, Vol. 17, No. 5, 01.10.2014, p. 470-476.

Research output: Contribution to journalArticle

Palmieri, Serena ; Morelli, Valentina ; Salcuni, Antonio Stefano ; Eller-Vainicher, Cristina ; Cairoli, Elisa ; Zhukouskaya, Volha V. ; Beck-Peccoz, Paolo ; Scillitani, Alfredo ; Chiodini, Iacopo. / GH secretion reserve in subclinical hypercortisolism. In: Pituitary. 2014 ; Vol. 17, No. 5. pp. 470-476.
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AU - Zhukouskaya, Volha V.

AU - Beck-Peccoz, Paolo

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