Giant cell myocarditis successfully treated with antithymocyte globuline and extracorporeal membrane oxygenation for 21 days

Enrico Ammirati, Fabrizio Oliva, Oriana Belli, Edgardo Bonacina, Patrizia Pedrotti, Fabio Maria Turazza, Alberto Roghi, Roberto Paino, Luigi Martinelli, Maria Frigerio

Research output: Contribution to journalArticlepeer-review

Abstract

A 31-year-old man presenting with cardiogenic shock and left ventricular ejection fraction of 10% received the diagnosis of giant cell myocarditis by endomyocardial biopsy. The patient was successfully treated with high-dose inotropes, intra-aortic balloon pump and venoarterial extracorporeal membrane oxygenation for 21 days associated with combined immunosuppression (thymoglobulin, steroids, cyclosporine). Immunosuppression including thymoglobulin is the regimen associated with the highest probability of recovery in case of giant cell myocarditis. Immunosuppression needs time to be effective; thus, hemodynamic support must be guaranteed. In the present case, we observed that full recovery can be obtained up to 21 days of support with extracorporeal membrane oxygenation and adequate immunosuppression.

Original languageEnglish
JournalJournal of Cardiovascular Medicine
DOIs
Publication statusAccepted/In press - Jan 31 2015

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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