Giant congenital nevus and chronic progressive ascending hemiparesis (Mills syndrome). Report of a case

G. B. Frisoni, R. Gasparotti, V. Di Monda

Research output: Contribution to journalArticle


We describe the case of a 20 year old boy with a giant congenital nevus who developed a chronic progressive ascending hemiparesis. The association of the pigmented lesion with a focal neurological deficit is pathognomonic for neurocutaneous melanosis complicated by a leptomeningeal melanoma. MR imaging at 1.5 tesla ruled out such a possiblity and showed a small aspecific pontine lesion along the route of the corticospinal tract. We discuss possible etiologies.

Original languageEnglish
Pages (from-to)259-263
Number of pages5
JournalItalian Journal of Neurological Sciences
Issue number3
Publication statusPublished - Apr 1992



  • chronic hemiparesis
  • Giant nevus
  • Mills syndrome
  • neurocutaneous melanosis
  • phakomatosis
  • primary lateral sclerosis

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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