Gilles de la Tourette syndrome and voluntary movement: A functional MRI study

Francesco Fattapposta, Rita Restuccia, Claudio Colonnese, Ludovica Labruna, Girolamo Garreffa, Federico Bianco

Research output: Contribution to journalArticlepeer-review


Tourette syndrome (TS) is hypothesised to be caused by an abnormal organization of movement control. The aim of this study was to use functional magnetic resonance imaging to study motor cortex activation in a TS patient. Usual and unusual self-paced voluntary movements were performed. The TS patient displayed supplementary motor area (SMA) activation during both tasks. This activation reflects a continuous use of the SMA to perform the voluntary motor movements required in both tasks. Moreover, the absence of tics during the execution of these voluntary motor tasks suggests that tic activity may be suppressed by additional mental effort.

Original languageEnglish
Pages (from-to)269-272
Number of pages4
JournalPsychiatry Research - Neuroimaging
Issue number3
Publication statusPublished - Apr 30 2005


  • Functional magnetic resonance imaging
  • Motor task paradigm
  • Supplementary motor area
  • Tourette's syndrome
  • Voluntary movement

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Radiology Nuclear Medicine and imaging
  • Biological Psychiatry
  • Psychology(all)


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