Gilles de la Tourette syndrome and voluntary movement: A functional MRI study

Francesco Fattapposta, Rita Restuccia, Claudio Colonnese, Ludovica Labruna, Girolamo Garreffa, Federico Bianco

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Tourette syndrome (TS) is hypothesised to be caused by an abnormal organization of movement control. The aim of this study was to use functional magnetic resonance imaging to study motor cortex activation in a TS patient. Usual and unusual self-paced voluntary movements were performed. The TS patient displayed supplementary motor area (SMA) activation during both tasks. This activation reflects a continuous use of the SMA to perform the voluntary motor movements required in both tasks. Moreover, the absence of tics during the execution of these voluntary motor tasks suggests that tic activity may be suppressed by additional mental effort.

Original languageEnglish
Pages (from-to)269-272
Number of pages4
JournalPsychiatry Research - Neuroimaging
Volume138
Issue number3
DOIs
Publication statusPublished - Apr 30 2005

Fingerprint

Tourette Syndrome
Motor Cortex
Tics
Magnetic Resonance Imaging
Dyskinesias

Keywords

  • Functional magnetic resonance imaging
  • Motor task paradigm
  • Supplementary motor area
  • Tourette's syndrome
  • Voluntary movement

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Radiology Nuclear Medicine and imaging
  • Biological Psychiatry
  • Psychology(all)

Cite this

Gilles de la Tourette syndrome and voluntary movement : A functional MRI study. / Fattapposta, Francesco; Restuccia, Rita; Colonnese, Claudio; Labruna, Ludovica; Garreffa, Girolamo; Bianco, Federico.

In: Psychiatry Research - Neuroimaging, Vol. 138, No. 3, 30.04.2005, p. 269-272.

Research output: Contribution to journalArticle

Fattapposta, Francesco ; Restuccia, Rita ; Colonnese, Claudio ; Labruna, Ludovica ; Garreffa, Girolamo ; Bianco, Federico. / Gilles de la Tourette syndrome and voluntary movement : A functional MRI study. In: Psychiatry Research - Neuroimaging. 2005 ; Vol. 138, No. 3. pp. 269-272.
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