Gingival lesions in a patient with dermochondrocorneal dystrophy (François syndrome). A case report

Andrea Sardella, Antonio Carrassi, Ruggero Caputo, Marcello Monti, Paolo Gotte

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This report is concerned with gingival manifestations associated with a case of dermochondrocorneal dystrophy (DCCD) or François syndrome occurring in a 42-year-old woman. Our Department treated this patient for 15 years. Oral examination of this case revealed a diffuse enlargement and severe inflammation of the attached gingiva. Systemic findings were similar to those reported in the literature for patients with DCCD. Firm papules 3 mm wide, localized on the face and on the dorsal surface of the hands, were associated with corneal involvement and progressive and severe articular disorder. Because they recurred after surgical ablation, the gingival lesions became an important problem in the management of the patient. After 10 years of unsuccessful treatment limited to scaling, oral hygiene control and mouth rinses with 0.2% chlorexidine solution, the patient was submitted to extraction of the remaining teeth, remodelling osteoplasty and cutaneous graft. An acrylic full denture was inserted. In a follow-up of 7 years, good results for the oral health of the patient were seen. & Munksgaard, 1998.

Original languageEnglish
Pages (from-to)1047-1049
Number of pages3
JournalJournal of Clinical Periodontology
Issue number12
Publication statusPublished - Dec 1998


  • Dermochondrocorneal dystrophy
  • François syndrome
  • Gingival enlargement
  • Gingivitis
  • Multicentric reticulohistiocytosis

ASJC Scopus subject areas

  • Dentistry(all)


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