Abstract
Five patients who developed an intracranial glioblastoma after a kidney transplant are described. All patients underwent surgical removal of the lesion and eventually radiation therapy, but none of them is still alive at follow-up. The possibility of tumours occurring in transplant recipients is a recognised entity and several series have been reported. Nevertheless, little consideration has been paid to post-transplant gliomas and a precise evaluation of this risk is still lacking. Several hypotheses have been proposed to explain a possible link. One possible factor may be the immunosuppressive state of recipients as a result of post-transplant administration of immunosuppressive drugs, as it is known that gliomas have an higher incidence in HIV-infected patients. However, it is not yet clear whether immunosuppressive drugs function as a direct transforming factor.
Original language | English |
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Pages (from-to) | 33-37 |
Number of pages | 5 |
Journal | Journal of Neuro-Oncology |
Volume | 63 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2003 |
Keywords
- Gliomas
- Post-transplant
- Transplant
- Tumours
ASJC Scopus subject areas
- Clinical Neurology
- Cancer Research
- Oncology
- Neurology