Glioblastoma multiforme and breast cancer

Report on 11 cases and clinico-pathological remarks

Manolo Piccirilli, Maurizio Salvati, Simona Bistazzoni, Alessandro Frati, Christian Brogna, Felice Giangaspero, Riccardo Frati, Antonio Santoro

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The association between breast cancer and glioblastoma multiforme has not been amply analyzed in the literature. We describe 11 female patients with a diagnosis of glioblastoma multiforme who were treated when younger for breast cancer. We believe that this association is not due to chance but rather to genetic changes in hormone status and in particular to sex hormones. Another important point of view is represented by the chemotherapy treatment of breast cancer, which could have a carcinogenic effect and explain the growth of glioblastoma. This consideration, in our opinion, is important, because more effort should be made to understand the pathogenesis of glioblastoma multiforme and to improve the therapeutic approaches.

Original languageEnglish
Pages (from-to)256-260
Number of pages5
JournalTumori
Volume91
Issue number3
Publication statusPublished - May 2005

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Glioblastoma
Breast Neoplasms
Gonadal Steroid Hormones
Hormones
Drug Therapy
Therapeutics
Growth

Keywords

  • Breast cancer
  • Chemotherapy
  • Glioblastoma multiforme
  • Radiotherapy
  • Secondary malignancies
  • Surgery

ASJC Scopus subject areas

  • Cancer Research

Cite this

Piccirilli, M., Salvati, M., Bistazzoni, S., Frati, A., Brogna, C., Giangaspero, F., ... Santoro, A. (2005). Glioblastoma multiforme and breast cancer: Report on 11 cases and clinico-pathological remarks. Tumori, 91(3), 256-260.

Glioblastoma multiforme and breast cancer : Report on 11 cases and clinico-pathological remarks. / Piccirilli, Manolo; Salvati, Maurizio; Bistazzoni, Simona; Frati, Alessandro; Brogna, Christian; Giangaspero, Felice; Frati, Riccardo; Santoro, Antonio.

In: Tumori, Vol. 91, No. 3, 05.2005, p. 256-260.

Research output: Contribution to journalArticle

Piccirilli, M, Salvati, M, Bistazzoni, S, Frati, A, Brogna, C, Giangaspero, F, Frati, R & Santoro, A 2005, 'Glioblastoma multiforme and breast cancer: Report on 11 cases and clinico-pathological remarks', Tumori, vol. 91, no. 3, pp. 256-260.
Piccirilli, Manolo ; Salvati, Maurizio ; Bistazzoni, Simona ; Frati, Alessandro ; Brogna, Christian ; Giangaspero, Felice ; Frati, Riccardo ; Santoro, Antonio. / Glioblastoma multiforme and breast cancer : Report on 11 cases and clinico-pathological remarks. In: Tumori. 2005 ; Vol. 91, No. 3. pp. 256-260.
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