Glioblastoma: Prognostic factors and predictive response to radio-and chemotherapy

Francesco Fiorica, Maria Colella, Rosaria Taibi, Andrea Bonetti, Jacopo Giuliani, Maria Sole Perrone, Sonia Missiroli, Carlotta Giorgi

Research output: Contribution to journalReview articlepeer-review

Abstract

Glioblastoma multiforme (GBM) is characterized by poor prognosis despite an aggressive therapeutic strategy. In recent years, many advances have been achieved in the field of glioblastoma biology. Here we try to summarize the main clinical and biological factors impacting clinical prog-nostication and therapy of GBM patients. From that standpoint, hopefully, in the near future, personalized therapies will be available.

Original languageEnglish
Pages (from-to)2814-2825
Number of pages12
JournalCurrent Medicinal Chemistry
Volume27
Issue number17
DOIs
Publication statusPublished - 2020

Keywords

  • Glioblastoma
  • Glioblastoma multiforme (GBM)
  • Predictive response
  • Prognostic factor

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Pharmacology
  • Drug Discovery
  • Organic Chemistry

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