Gliomas of cerebral hemispheres in children

S. M. Gaini, C. Arienta, M. Zavanone

Research output: Contribution to journalArticlepeer-review

Abstract

This study includes 94 children ranging between 4 months and 16 years of age. Surgery is the treatment of choice for hemisphere gliomas in children. The overall operative mortality is at present very low. Moreover, surgery allows a careful histological evaluation ensuring an essential guide to prognosis. Removal should be as radical as possible. In our follow-ups 5 years after surgery, 53% of patients with radical resection were alive, whereas only 33% of the patients with incomplete extirpation had survived. Moreover, the well-known plasticity of the brain in children allows complete removal of larger tumours with less severe neurological sequelae than in adults. Comparing survival rates of the same oncotype in children and adults, we noticed that children had a much better outcome, so much so that we believe that in some cases of astrocytoma, these patients could be considered completely cured. Radiotherapy should be used in all malignant neoplasms. But in astrocytomas (which constitute 47% of all children with gliomas of the hemisphere), irradiation remains controversial because of the very low sensitivity to X-rays and the risk of irradiating the brain of the children.

Original languageEnglish
Pages (from-to)196-197
Number of pages2
JournalZeitschrift fur Kinderchirurgie
Volume34
Issue number2
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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