Gliomatosis cerebri treatment in 11 elderly patients

M. Piccirilli, A. Landi, M. Salvati

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The Authors report their experience in the treatment of eleven patients over 70 years old (range from 70 to 83, average age 74.8, 7 males and 4 females), with histologically proven diagnosis of glioblastoma multiforme. The GC golden standard treatment is still debated, particularly in elderly patients. All the patients underwent a first line treatment with chemotherapy (Temozolomide), followed by Whole Brain Radiotherapy (WBRT) and PCV schedule without Vincristine in case of progression of the disease. The median survival was 16.3 months, ranging from 13 to 22 months. According to our experience, elderly patients should undergo the same treatment of younger patients, provided they are in good health conditions.

Original languageEnglish
Pages (from-to)183-187
Number of pages5
JournalJournal of Experimental and Clinical Cancer Research
Volume25
Issue number2
Publication statusPublished - Jun 2006

Fingerprint

Neuroepithelial Neoplasms
temozolomide
Therapeutics
Vincristine
Glioblastoma
Disease Progression
Appointments and Schedules
Radiotherapy
Drug Therapy
Survival
Health
Brain

Keywords

  • Elderly patients
  • Gliomatosis cerebri
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Gliomatosis cerebri treatment in 11 elderly patients. / Piccirilli, M.; Landi, A.; Salvati, M.

In: Journal of Experimental and Clinical Cancer Research, Vol. 25, No. 2, 06.2006, p. 183-187.

Research output: Contribution to journalArticle

Piccirilli, M, Landi, A & Salvati, M 2006, 'Gliomatosis cerebri treatment in 11 elderly patients', Journal of Experimental and Clinical Cancer Research, vol. 25, no. 2, pp. 183-187.
Piccirilli, M. ; Landi, A. ; Salvati, M. / Gliomatosis cerebri treatment in 11 elderly patients. In: Journal of Experimental and Clinical Cancer Research. 2006 ; Vol. 25, No. 2. pp. 183-187.
@article{3832dee055e14dcb9878f1ef8dc70a73,
title = "Gliomatosis cerebri treatment in 11 elderly patients",
abstract = "The Authors report their experience in the treatment of eleven patients over 70 years old (range from 70 to 83, average age 74.8, 7 males and 4 females), with histologically proven diagnosis of glioblastoma multiforme. The GC golden standard treatment is still debated, particularly in elderly patients. All the patients underwent a first line treatment with chemotherapy (Temozolomide), followed by Whole Brain Radiotherapy (WBRT) and PCV schedule without Vincristine in case of progression of the disease. The median survival was 16.3 months, ranging from 13 to 22 months. According to our experience, elderly patients should undergo the same treatment of younger patients, provided they are in good health conditions.",
keywords = "Elderly patients, Gliomatosis cerebri, Magnetic resonance imaging",
author = "M. Piccirilli and A. Landi and M. Salvati",
year = "2006",
month = "6",
language = "English",
volume = "25",
pages = "183--187",
journal = "Journal of Experimental and Clinical Cancer Research",
issn = "0392-9078",
publisher = "BioMed Central Ltd.",
number = "2",

}

TY - JOUR

T1 - Gliomatosis cerebri treatment in 11 elderly patients

AU - Piccirilli, M.

AU - Landi, A.

AU - Salvati, M.

PY - 2006/6

Y1 - 2006/6

N2 - The Authors report their experience in the treatment of eleven patients over 70 years old (range from 70 to 83, average age 74.8, 7 males and 4 females), with histologically proven diagnosis of glioblastoma multiforme. The GC golden standard treatment is still debated, particularly in elderly patients. All the patients underwent a first line treatment with chemotherapy (Temozolomide), followed by Whole Brain Radiotherapy (WBRT) and PCV schedule without Vincristine in case of progression of the disease. The median survival was 16.3 months, ranging from 13 to 22 months. According to our experience, elderly patients should undergo the same treatment of younger patients, provided they are in good health conditions.

AB - The Authors report their experience in the treatment of eleven patients over 70 years old (range from 70 to 83, average age 74.8, 7 males and 4 females), with histologically proven diagnosis of glioblastoma multiforme. The GC golden standard treatment is still debated, particularly in elderly patients. All the patients underwent a first line treatment with chemotherapy (Temozolomide), followed by Whole Brain Radiotherapy (WBRT) and PCV schedule without Vincristine in case of progression of the disease. The median survival was 16.3 months, ranging from 13 to 22 months. According to our experience, elderly patients should undergo the same treatment of younger patients, provided they are in good health conditions.

KW - Elderly patients

KW - Gliomatosis cerebri

KW - Magnetic resonance imaging

UR - http://www.scopus.com/inward/record.url?scp=33746384078&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33746384078&partnerID=8YFLogxK

M3 - Article

C2 - 16918128

AN - SCOPUS:33746384078

VL - 25

SP - 183

EP - 187

JO - Journal of Experimental and Clinical Cancer Research

JF - Journal of Experimental and Clinical Cancer Research

SN - 0392-9078

IS - 2

ER -