Abstract
Background Information on physical performance in renal transplantation is limited because of the shortage of specifically designed evaluation instruments. Therefore, we elaborated and validated the Global Performance Status (GloPerSta) score to provide a new and comprehensive tool, exploring the different components of physical performance in kidney transplant patients. Methods We elaborated the GloPerSta score on the basis of the data obtained from a cross-sectional study, in which we evaluated the physical performance of a cohort of kidney transplant patients. The results of these analyses were weighted to describe the different contribution of any single test, via the generation of a structural equation model, resulting in the definition of the GloPerSta. Then, to internally validate this score, we studied its correlation with clinical parameters and quality of life (evaluated as KDQOL-SF, Kidney Disease Quality of Life-Short Form) in the same patient population. Results We enrolled 132 patients in whom the functional tests revealed a great heterogeneity. GloPerSta allowed the stratification of the patients in 3 different physical performance categories (low: score 0–11; medium: 12–22; high: 23–33). Internal validation showed that GloPerSta was directly and significantly correlated with the quality of life and allograft function, independent of the time from transplantation. Conclusions The GloPerSta is a reliable tool to assess physical performance in a kidney transplant population. Its application might be of help in identifying patients needing intensive and personalized rehabilitation programs.
| Original language | English |
|---|---|
| Pages (from-to) | 1270-1275 |
| Number of pages | 6 |
| Journal | Transplantation Proceedings |
| Volume | 49 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jul 1 2017 |
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ASJC Scopus subject areas
- Surgery
- Transplantation
Cite this
Global Performance Status Score : A New Tool to Assess Physical Performance in Kidney Transplant Patients. / Esposito, P.; Furini, F.; Gregorini, M.; Pattonieri, E. F.; Corradetti, V.; La Porta, E.; Caramella, E.; Calatroni, M.; Petrucci, L.; Klersy, C.; Rampino, T.
In: Transplantation Proceedings, Vol. 49, No. 6, 01.07.2017, p. 1270-1275.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Global Performance Status Score
T2 - A New Tool to Assess Physical Performance in Kidney Transplant Patients
AU - Esposito, P.
AU - Furini, F.
AU - Gregorini, M.
AU - Pattonieri, E. F.
AU - Corradetti, V.
AU - La Porta, E.
AU - Caramella, E.
AU - Calatroni, M.
AU - Petrucci, L.
AU - Klersy, C.
AU - Rampino, T.
PY - 2017/7/1
Y1 - 2017/7/1
N2 - Background Information on physical performance in renal transplantation is limited because of the shortage of specifically designed evaluation instruments. Therefore, we elaborated and validated the Global Performance Status (GloPerSta) score to provide a new and comprehensive tool, exploring the different components of physical performance in kidney transplant patients. Methods We elaborated the GloPerSta score on the basis of the data obtained from a cross-sectional study, in which we evaluated the physical performance of a cohort of kidney transplant patients. The results of these analyses were weighted to describe the different contribution of any single test, via the generation of a structural equation model, resulting in the definition of the GloPerSta. Then, to internally validate this score, we studied its correlation with clinical parameters and quality of life (evaluated as KDQOL-SF, Kidney Disease Quality of Life-Short Form) in the same patient population. Results We enrolled 132 patients in whom the functional tests revealed a great heterogeneity. GloPerSta allowed the stratification of the patients in 3 different physical performance categories (low: score 0–11; medium: 12–22; high: 23–33). Internal validation showed that GloPerSta was directly and significantly correlated with the quality of life and allograft function, independent of the time from transplantation. Conclusions The GloPerSta is a reliable tool to assess physical performance in a kidney transplant population. Its application might be of help in identifying patients needing intensive and personalized rehabilitation programs.
AB - Background Information on physical performance in renal transplantation is limited because of the shortage of specifically designed evaluation instruments. Therefore, we elaborated and validated the Global Performance Status (GloPerSta) score to provide a new and comprehensive tool, exploring the different components of physical performance in kidney transplant patients. Methods We elaborated the GloPerSta score on the basis of the data obtained from a cross-sectional study, in which we evaluated the physical performance of a cohort of kidney transplant patients. The results of these analyses were weighted to describe the different contribution of any single test, via the generation of a structural equation model, resulting in the definition of the GloPerSta. Then, to internally validate this score, we studied its correlation with clinical parameters and quality of life (evaluated as KDQOL-SF, Kidney Disease Quality of Life-Short Form) in the same patient population. Results We enrolled 132 patients in whom the functional tests revealed a great heterogeneity. GloPerSta allowed the stratification of the patients in 3 different physical performance categories (low: score 0–11; medium: 12–22; high: 23–33). Internal validation showed that GloPerSta was directly and significantly correlated with the quality of life and allograft function, independent of the time from transplantation. Conclusions The GloPerSta is a reliable tool to assess physical performance in a kidney transplant population. Its application might be of help in identifying patients needing intensive and personalized rehabilitation programs.
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UR - http://www.scopus.com/inward/citedby.url?scp=85024877126&partnerID=8YFLogxK
U2 - 10.1016/j.transproceed.2017.02.052
DO - 10.1016/j.transproceed.2017.02.052
M3 - Article
VL - 49
SP - 1270
EP - 1275
JO - Transplantation Proceedings
JF - Transplantation Proceedings
SN - 0041-1345
IS - 6
ER -