LEUCODISTROFIA A CELLULE GLOBOIDI (MALATTIA DI KRABBE): REPERTI US IN 2 PAZIENTI E CORRELAZIONE TC E RM

Translated title of the contribution: Globoid cell leukodystrophy (Krabbe disease): US patterns in two patients and CT and MRI correlation

G. Fariello, C. Orazi, S. Malena, C. Dionisi Vici, G. Sabetta, E. Bertini

Research output: Contribution to journalArticle

Abstract

Krabbe disease (globoid cell leukodystrophy) is an early onset progressive ezncephalopathy due to deficiency of galactocerebroside-beta-galactosidase. CT and MR imaging show involvement (demyelination) of white matter and of thalami. CT findings are somewhat earlier, with a typical hyperdensity of thalami and cerebellum. We performed cranial us in 2 infants with Krabbe disease. We found increased echogenicity of periventricular white matter and of thalamic regions. This US pattern, when associated with typical clues of Krabbe disease, may be helpful for an early diagnosis.

Original languageItalian
Pages (from-to)262-263
Number of pages2
JournalRivista di Neuroradiologia
Volume7
Issue number2
Publication statusPublished - 1994

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ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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