Glucocorticoids in juvenile idiopathic arthritis

Research output: Contribution to journalArticlepeer-review

Abstract

Although the use of corticosteroids in juvenile idiopathic arthritis (JIA) is now much more limited owing to the availability of methotrexate and biological agents, there are clinical scenarios where it is still indicated. For example, corticosteroids may be indicated for intraarticular injections to prevent joint deformities, as a "bridge" drug to relieve symptoms in polyarticular disease while waiting for methotrexate and biologics to exert their full therapeutic effects, and in the treatment of chronic iridocyclitis, macrophage activation syndrome, and systemic JIA, although the advent of interleukin (IL)-1 and IL-6 blockers has greatly reduced the latter indication.

Original languageEnglish
Pages (from-to)65-70
Number of pages6
JournalAnnals of the New York Academy of Sciences
Volume1318
Issue number1
DOIs
Publication statusPublished - 2014

Keywords

  • Chronic iridocyclitis
  • Corticosteroids
  • Intraarticular injections
  • Juvenile idiopathic arthritis
  • Macrophage activation syndrome
  • Systemic juvenile idiopathic arthritis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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