Glucose Metabolism Abnormalities in Heart Failure Patients: Insights and Prognostic Relevance

Fabio Marsico, Paola Gargiulo, Alberto M. Marra, Antonio Parente, Stefania Paolillo

Research output: Contribution to journalReview articlepeer-review


Heart failure is a clinical syndrome characterized by left ventricular dysfunction and/or elevated intracardiac pressures, with a prevalence of about 1% to 2% in the general population. In the last decades, many metabolic disorders have been studied as linked with heart failure. Diabetes mellitus and insulin resistance are strictly related to heart failure, with a bidirectional link, where each can influence the other. The aim of this article is to report the role of glucose metabolism abnormalities in the development of heart failure, defining the epidemiology and assessing pathophysiology and prognosis of heart failure related to glucose metabolism disorders.

Original languageEnglish
Pages (from-to)333-340
Number of pages8
JournalHeart Failure Clinics
Issue number3
Publication statusPublished - Jul 2019


  • Diabetes mellitus
  • Glucose metabolism abnormalities
  • Heart failure
  • Hyperglycemia
  • Insulin resistance
  • Insulin sensitivity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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