GluR3 antibodies: Prevalence in focal epilepsy but no specificity for Rasmussen's encephalitis

Heinz Wiendl, C. G. Bien, P. Bernasconi, B. Fleckenstein, C. E. Elger, J. Dichgans, R. Mantegazza, A. Melms

Research output: Contribution to journalArticlepeer-review

Abstract

Eight patients with Rasmussen's encephalitis, 40 patients with noninflammatory focal epilepsy, 104 patients with various neurologic diseases, and 16 healthy donors were tested for the prevalence of antibodies against the GluR3 receptor in serum and CSF. Reactivities against different peptides derived from various portions of this glutamate receptor subtype were detectable in a significantly higher number of patients with focal epilepsy than in those with other neurologic diseases, but they were not specific for the diagnosis of Rasmussen's encephalitis.

Original languageEnglish
Pages (from-to)1511-1514
Number of pages4
JournalNeurology
Volume57
Issue number8
Publication statusPublished - Oct 23 2001

ASJC Scopus subject areas

  • Neuroscience(all)

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