Abstract
Monosodium glutamate (MSG) administered orally at 4 g/kg body weight (b.wt.) as a 20% solution (w/v) to 55-60-day-old guinea pigs and at 2 g/kg b.wt. as a 20% solution (w/v) to 3-day-old guinea pigs did not increase glutamie acid (GA) or sodium levels in the nucleus arcuatus of the hypothalamus (NAH) or in the thalamus lateralis (TL). Sodium chloride given by gavage at doses of sodium equimolar to MSG resulted in an increase of sodium content only in the NAH of infant guinea pigs.
| Original language | English |
|---|---|
| Pages (from-to) | 313-316 |
| Number of pages | 4 |
| Journal | Toxicology Letters |
| Volume | 4 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1979 |
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ASJC Scopus subject areas
- Toxicology
Cite this
Glutamic acid and sodium levels in the nucleus arcuatus of the hypothalamus of adult and infant guinea pigs after oral monosodium glutamate. / Airoldi, L.; Garattini, S.
In: Toxicology Letters, Vol. 4, No. 4, 1979, p. 313-316.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Glutamic acid and sodium levels in the nucleus arcuatus of the hypothalamus of adult and infant guinea pigs after oral monosodium glutamate
AU - Airoldi, L.
AU - Garattini, S.
PY - 1979
Y1 - 1979
N2 - Monosodium glutamate (MSG) administered orally at 4 g/kg body weight (b.wt.) as a 20% solution (w/v) to 55-60-day-old guinea pigs and at 2 g/kg b.wt. as a 20% solution (w/v) to 3-day-old guinea pigs did not increase glutamie acid (GA) or sodium levels in the nucleus arcuatus of the hypothalamus (NAH) or in the thalamus lateralis (TL). Sodium chloride given by gavage at doses of sodium equimolar to MSG resulted in an increase of sodium content only in the NAH of infant guinea pigs.
AB - Monosodium glutamate (MSG) administered orally at 4 g/kg body weight (b.wt.) as a 20% solution (w/v) to 55-60-day-old guinea pigs and at 2 g/kg b.wt. as a 20% solution (w/v) to 3-day-old guinea pigs did not increase glutamie acid (GA) or sodium levels in the nucleus arcuatus of the hypothalamus (NAH) or in the thalamus lateralis (TL). Sodium chloride given by gavage at doses of sodium equimolar to MSG resulted in an increase of sodium content only in the NAH of infant guinea pigs.
UR - http://www.scopus.com/inward/record.url?scp=0343771690&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0343771690&partnerID=8YFLogxK
U2 - 10.1016/0378-4274(79)90072-9
DO - 10.1016/0378-4274(79)90072-9
M3 - Article
AN - SCOPUS:0343771690
VL - 4
SP - 313
EP - 316
JO - Toxicology Letters
JF - Toxicology Letters
SN - 0378-4274
IS - 4
ER -