Gluten-Free Diet in Celiac Disease-Forever and for All?

Alice Itzlinger, Federica Branchi, Luca Elli, Michael Schumann

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

The gluten-free diet is the only effective treatment available for celiac disease. However, it is difficult to adhere to and a closer look on the diet's implementation and indications reveals several ambiguities: Not only is there controversy on the threshold of gluten that can be tolerated in the frame of a strict gluten-free diet, but it is also unclear whether the gluten-free diet is an appropriate treatment in patient subgroups with asymptomatic or potential celiac disease. Reports from a number of research groups suggest that a certain proportion of patients may effectively develop tolerance to gluten and thus become suitable for gluten reintroduction over time. In this review, we set out to create an overview about the current state of research as regards the definition of a strict gluten-free diet in terms of the gluten thresholds considered tolerable and the indication for a gluten-free diet in the absence of histological abnormalities or symptoms. Furthermore, we discuss the concept that a gluten-free diet must be followed for life by all patients.

Original languageEnglish
Article numberE1796
JournalNutrients
Volume10
Issue number11
DOIs
Publication statusPublished - Nov 18 2018

Fingerprint

gluten-free diet
Gluten-Free Diet
celiac disease
Celiac Disease
Glutens
gluten
Research
signs and symptoms (animals and humans)
Diet
Therapeutics
diet

Keywords

  • adherence
  • gluten
  • mucosal recovery
  • serology
  • threshold
  • villous atrophy

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics

Cite this

Gluten-Free Diet in Celiac Disease-Forever and for All? / Itzlinger, Alice; Branchi, Federica; Elli, Luca; Schumann, Michael.

In: Nutrients, Vol. 10, No. 11, E1796, 18.11.2018.

Research output: Contribution to journalReview article

Itzlinger, A, Branchi, F, Elli, L & Schumann, M 2018, 'Gluten-Free Diet in Celiac Disease-Forever and for All?', Nutrients, vol. 10, no. 11, E1796. https://doi.org/10.3390/nu10111796
Itzlinger, Alice ; Branchi, Federica ; Elli, Luca ; Schumann, Michael. / Gluten-Free Diet in Celiac Disease-Forever and for All?. In: Nutrients. 2018 ; Vol. 10, No. 11.
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