Glycemic control with an artificial pancreas improves insulin responses to both oral and I.V. Glucose in nonobese noninsulin-dependent diabetic subjects

Dario Giugliano, Paolo Di Pinto, Antonio Ceriello, Giuseppe Paolisso, Franco Saccomanno, Roberto Torella, Felice D'Onofrio

Research output: Contribution to journalArticlepeer-review

Abstract

Insulin secretory responses to both oral and intravenous glucose were investigated in 12 nonobese noninsulin-dependent diabetic subjects before and after strict metabolic control of blood glucose levels without weight loss. Glycemic control was achieved by applying an artificial pancreas to all diabetics for 2 or 3 days, which led to restoration of normal fasting blood glucose levels and to significant reduction of fasting plasma insulin (p

Original languageEnglish
Pages (from-to)203-213
Number of pages11
JournalActa Diabetologica Latina
Volume22
Issue number3
DOIs
Publication statusPublished - Jul 1985

Keywords

  • Artificial pancreas
  • Glycemic control
  • Improved insulin secretion
  • Insulin responses to glucose
  • Noninsulin-dependent diabetes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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