Glycemic control with an artificial pancreas improves insulin responses to both oral and I.V. Glucose in nonobese noninsulin-dependent diabetic subjects

Dario Giugliano; Paolo Di Pinto; Antonio Ceriello; Giuseppe Paolisso; Franco Saccomanno; Roberto Torella; Felice D'Onofrio

doi:10.1007/BF02590771

Glycemic control with an artificial pancreas improves insulin responses to both oral and I.V. Glucose in nonobese noninsulin-dependent diabetic subjects

Dario Giugliano, Paolo Di Pinto, Antonio Ceriello, Giuseppe Paolisso, Franco Saccomanno, Roberto Torella, Felice D'Onofrio

IRCCS Multimedica

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Abstract

Insulin secretory responses to both oral and intravenous glucose were investigated in 12 nonobese noninsulin-dependent diabetic subjects before and after strict metabolic control of blood glucose levels without weight loss. Glycemic control was achieved by applying an artificial pancreas to all diabetics for 2 or 3 days, which led to restoration of normal fasting blood glucose levels and to significant reduction of fasting plasma insulin (p

Original language	English
Pages (from-to)	203-213
Number of pages	11
Journal	Acta Diabetologica Latina
Volume	22
Issue number	3
DOIs	https://doi.org/10.1007/BF02590771
Publication status	Published - Jul 1985

Keywords

Artificial pancreas
Glycemic control
Improved insulin secretion
Insulin responses to glucose
Noninsulin-dependent diabetes

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1007/BF02590771

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keywords = "Artificial pancreas, Glycemic control, Improved insulin secretion, Insulin responses to glucose, Noninsulin-dependent diabetes",

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AU - Ceriello, Antonio

AU - Paolisso, Giuseppe

AU - Saccomanno, Franco

AU - Torella, Roberto

AU - D'Onofrio, Felice

PY - 1985/7

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AB - Insulin secretory responses to both oral and intravenous glucose were investigated in 12 nonobese noninsulin-dependent diabetic subjects before and after strict metabolic control of blood glucose levels without weight loss. Glycemic control was achieved by applying an artificial pancreas to all diabetics for 2 or 3 days, which led to restoration of normal fasting blood glucose levels and to significant reduction of fasting plasma insulin (p

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KW - Improved insulin secretion

KW - Insulin responses to glucose

KW - Noninsulin-dependent diabetes

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Glycemic control with an artificial pancreas improves insulin responses to both oral and I.V. Glucose in nonobese noninsulin-dependent diabetic subjects

Abstract

Keywords

ASJC Scopus subject areas

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