Abstract
The aim of this study was to evaluate the glyco-metabolic profile among type 2 diabetic patients with erectile dysfunction (ED). We evaluated 88 type 2 diabetic males, aged 62.78±9.26 years. We administered patients the IIEF (International Index of Erectile Function) questionnaire to assess erectile function, organ function, sexual desire, and satisfaction level during and after the sexual intercourse and the SAS (self-rating anxiety scale) and SDS (self-rating depression scale) questionnaires to evaluate anxiety and depression. We evaluated: BMI, abdominal circumference, glycated hemoglobin (HbA1c), fasting plasma glucose (FPG), fasting plasma insulin (FPI), HOMA index, lipid profile, testosterone, free testosterone, dihydrotestosterone, and sex hormone binding globulin (SHBG). The IIEF questionnaire showed that in the examined sample there were 50 patients (56.8%) affected by ED, and 38 patients (43.2%) without ED. Comparing the two groups, 57.9% of patients without ED, and 70.0% of patients with ED were smokers, and the difference between the two groups was significant (p1c. Furthermore, patients with ED had higher levels of FPI, and lower levels of testosterone and dihydrotestosterone. The prevalence of ED in Italian type 2 diabetic males with mean age of 62 years is about 56% and it is linked to higher levels of FPI, but lower levels of HbA1c, free testosterone and dihydrotestosterone.
| Original language | English |
|---|---|
| Pages (from-to) | 611-619 |
| Number of pages | 9 |
| Journal | Endocrine Journal |
| Volume | 59 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2012 |
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Keywords
- Erectile dysfunction
- Hyperinsulinemia
- International Index of Erectile Function (IIEF)
- Testosterone
- Type 2 diabetes mellitus
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
Cite this
Glyco-metabolic profile among type 2 diabetic patients with erectile dysfunction. / Derosa, Giuseppe; Tinelli, Carmine; D'Angelo, Angela; Ferrara, Gianluca; Bonaventura, Aldo; Bianchi, Lucio; Romano, Davide; Fogari, Elena; Maffioli, Pamela.
In: Endocrine Journal, Vol. 59, No. 7, 2012, p. 611-619.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Glyco-metabolic profile among type 2 diabetic patients with erectile dysfunction
AU - Derosa, Giuseppe
AU - Tinelli, Carmine
AU - D'Angelo, Angela
AU - Ferrara, Gianluca
AU - Bonaventura, Aldo
AU - Bianchi, Lucio
AU - Romano, Davide
AU - Fogari, Elena
AU - Maffioli, Pamela
PY - 2012
Y1 - 2012
N2 - The aim of this study was to evaluate the glyco-metabolic profile among type 2 diabetic patients with erectile dysfunction (ED). We evaluated 88 type 2 diabetic males, aged 62.78±9.26 years. We administered patients the IIEF (International Index of Erectile Function) questionnaire to assess erectile function, organ function, sexual desire, and satisfaction level during and after the sexual intercourse and the SAS (self-rating anxiety scale) and SDS (self-rating depression scale) questionnaires to evaluate anxiety and depression. We evaluated: BMI, abdominal circumference, glycated hemoglobin (HbA1c), fasting plasma glucose (FPG), fasting plasma insulin (FPI), HOMA index, lipid profile, testosterone, free testosterone, dihydrotestosterone, and sex hormone binding globulin (SHBG). The IIEF questionnaire showed that in the examined sample there were 50 patients (56.8%) affected by ED, and 38 patients (43.2%) without ED. Comparing the two groups, 57.9% of patients without ED, and 70.0% of patients with ED were smokers, and the difference between the two groups was significant (p1c. Furthermore, patients with ED had higher levels of FPI, and lower levels of testosterone and dihydrotestosterone. The prevalence of ED in Italian type 2 diabetic males with mean age of 62 years is about 56% and it is linked to higher levels of FPI, but lower levels of HbA1c, free testosterone and dihydrotestosterone.
AB - The aim of this study was to evaluate the glyco-metabolic profile among type 2 diabetic patients with erectile dysfunction (ED). We evaluated 88 type 2 diabetic males, aged 62.78±9.26 years. We administered patients the IIEF (International Index of Erectile Function) questionnaire to assess erectile function, organ function, sexual desire, and satisfaction level during and after the sexual intercourse and the SAS (self-rating anxiety scale) and SDS (self-rating depression scale) questionnaires to evaluate anxiety and depression. We evaluated: BMI, abdominal circumference, glycated hemoglobin (HbA1c), fasting plasma glucose (FPG), fasting plasma insulin (FPI), HOMA index, lipid profile, testosterone, free testosterone, dihydrotestosterone, and sex hormone binding globulin (SHBG). The IIEF questionnaire showed that in the examined sample there were 50 patients (56.8%) affected by ED, and 38 patients (43.2%) without ED. Comparing the two groups, 57.9% of patients without ED, and 70.0% of patients with ED were smokers, and the difference between the two groups was significant (p1c. Furthermore, patients with ED had higher levels of FPI, and lower levels of testosterone and dihydrotestosterone. The prevalence of ED in Italian type 2 diabetic males with mean age of 62 years is about 56% and it is linked to higher levels of FPI, but lower levels of HbA1c, free testosterone and dihydrotestosterone.
KW - Erectile dysfunction
KW - Hyperinsulinemia
KW - International Index of Erectile Function (IIEF)
KW - Testosterone
KW - Type 2 diabetes mellitus
UR - http://www.scopus.com/inward/record.url?scp=84865622881&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84865622881&partnerID=8YFLogxK
U2 - 10.1507/endocrj.EJ12-0117
DO - 10.1507/endocrj.EJ12-0117
M3 - Article
VL - 59
SP - 611
EP - 619
JO - Endocrine Journal
JF - Endocrine Journal
SN - 0918-8959
IS - 7
ER -