We performed hysteroscopic incision of uterine septum in 22 women with repeated abortion. The patients underwent surgery during the proliferative phase (group 1, 12 subjects) or 4 weeks after a subcutaneous goserelin (3.6 mg) depot injection (group 2, 10 subjects) to evaluate surgical and anatomic results in hypo-oestrogenic women. Metroplasty was performed with microscissors. After the operation the surgeon classified the intra-uterine operating conditions as unfavourable, usual or optimal. In group 1 the mean operating time was 19 min with a standard deviation (SD) of 5 min, compared with 13 min with a SD of 6 in group 2 (P = 0.02). The mean distension medium deficit was 620 ml with a SD of 175 in group 1 vs. 340 ml with a SD of 213 in group 2 (P = 0.003). One group 1 woman with partial uterine septum had a fundal perforation which was managed conservatively. The intra-uterine operating conditions were judged to be usual or optimal in 50% of cases in group 1 vs. 90% in group 2 (P = 0.04). At follow-up ultrasonography and hysteroscopy performed 2 months after surgery, a residual fundal notch ≥ 1 cm deep was detected and corrected in three patients in each group. In our series of hysteroscopic metroplasties, a single gonadotropin releasing hormone agonist depot injection improved the operating conditions, reducing the operating time and the distension fluid deficit. The anatomic results were comparable in the two study groups.
|Number of pages||5|
|Publication status||Published - 1993|
- gonadotropin releasing hormone agonist
- uterine malformations
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Obstetrics and Gynaecology