Abstract
We studied the non-specific responses of GH and PRL to gonadotropin releasing hormone (GnRH) in eleven male patients aged 18-30 in whom a diagnosis of acute schizophrenia was made according to Crow's criteria. GnRH administration was followed by a significant increase in plasma GH in five patients; plasma PRL increased in two patients. The two prolactin responders were also GH responders. Non-specific GH response was confirmed on repeated testing in two patients in whom GnRH stimulation was performed twice. During saline control, non-specific hormone responses were not observed. The abnormal hormone responses observed in acute schizophrenia are probably due to the disordered monoamine regulation characteristic of this condition.
Original language | English |
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Pages (from-to) | 481-484 |
Number of pages | 4 |
Journal | Psychoneuroendocrinology |
Volume | 10 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1985 |
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
- Psychiatry and Mental health
- Biological Psychiatry
- Endocrine and Autonomic Systems
- Psychology(all)