Gonadotropin releasing hormone elicits abnormal hormone responses in schizophrenia

L. Cantalamessa, A. Catania, A. Silva, A. Orsatti, P. Motta, C. L. Cazzullo

Research output: Contribution to journalArticle

Abstract

We studied the non-specific responses of GH and PRL to gonadotropin releasing hormone (GnRH) in eleven male patients aged 18-30 in whom a diagnosis of acute schizophrenia was made according to Crow's criteria. GnRH administration was followed by a significant increase in plasma GH in five patients; plasma PRL increased in two patients. The two prolactin responders were also GH responders. Non-specific GH response was confirmed on repeated testing in two patients in whom GnRH stimulation was performed twice. During saline control, non-specific hormone responses were not observed. The abnormal hormone responses observed in acute schizophrenia are probably due to the disordered monoamine regulation characteristic of this condition.

Original languageEnglish
Pages (from-to)481-484
Number of pages4
JournalPsychoneuroendocrinology
Volume10
Issue number4
DOIs
Publication statusPublished - 1985

Fingerprint

Gonadotropin-Releasing Hormone
Schizophrenia
Hormones
Crows
Prolactin

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Psychiatry and Mental health
  • Biological Psychiatry
  • Endocrine and Autonomic Systems
  • Psychology(all)

Cite this

Cantalamessa, L., Catania, A., Silva, A., Orsatti, A., Motta, P., & Cazzullo, C. L. (1985). Gonadotropin releasing hormone elicits abnormal hormone responses in schizophrenia. Psychoneuroendocrinology, 10(4), 481-484. https://doi.org/10.1016/0306-4530(85)90088-5

Gonadotropin releasing hormone elicits abnormal hormone responses in schizophrenia. / Cantalamessa, L.; Catania, A.; Silva, A.; Orsatti, A.; Motta, P.; Cazzullo, C. L.

In: Psychoneuroendocrinology, Vol. 10, No. 4, 1985, p. 481-484.

Research output: Contribution to journalArticle

Cantalamessa, L, Catania, A, Silva, A, Orsatti, A, Motta, P & Cazzullo, CL 1985, 'Gonadotropin releasing hormone elicits abnormal hormone responses in schizophrenia', Psychoneuroendocrinology, vol. 10, no. 4, pp. 481-484. https://doi.org/10.1016/0306-4530(85)90088-5
Cantalamessa, L. ; Catania, A. ; Silva, A. ; Orsatti, A. ; Motta, P. ; Cazzullo, C. L. / Gonadotropin releasing hormone elicits abnormal hormone responses in schizophrenia. In: Psychoneuroendocrinology. 1985 ; Vol. 10, No. 4. pp. 481-484.
@article{82df9bb0e8b7413d8cb11ad0159383f6,
title = "Gonadotropin releasing hormone elicits abnormal hormone responses in schizophrenia",
abstract = "We studied the non-specific responses of GH and PRL to gonadotropin releasing hormone (GnRH) in eleven male patients aged 18-30 in whom a diagnosis of acute schizophrenia was made according to Crow's criteria. GnRH administration was followed by a significant increase in plasma GH in five patients; plasma PRL increased in two patients. The two prolactin responders were also GH responders. Non-specific GH response was confirmed on repeated testing in two patients in whom GnRH stimulation was performed twice. During saline control, non-specific hormone responses were not observed. The abnormal hormone responses observed in acute schizophrenia are probably due to the disordered monoamine regulation characteristic of this condition.",
author = "L. Cantalamessa and A. Catania and A. Silva and A. Orsatti and P. Motta and Cazzullo, {C. L.}",
year = "1985",
doi = "10.1016/0306-4530(85)90088-5",
language = "English",
volume = "10",
pages = "481--484",
journal = "Psychoneuroendocrinology",
issn = "0306-4530",
publisher = "Elsevier Ltd",
number = "4",

}

TY - JOUR

T1 - Gonadotropin releasing hormone elicits abnormal hormone responses in schizophrenia

AU - Cantalamessa, L.

AU - Catania, A.

AU - Silva, A.

AU - Orsatti, A.

AU - Motta, P.

AU - Cazzullo, C. L.

PY - 1985

Y1 - 1985

N2 - We studied the non-specific responses of GH and PRL to gonadotropin releasing hormone (GnRH) in eleven male patients aged 18-30 in whom a diagnosis of acute schizophrenia was made according to Crow's criteria. GnRH administration was followed by a significant increase in plasma GH in five patients; plasma PRL increased in two patients. The two prolactin responders were also GH responders. Non-specific GH response was confirmed on repeated testing in two patients in whom GnRH stimulation was performed twice. During saline control, non-specific hormone responses were not observed. The abnormal hormone responses observed in acute schizophrenia are probably due to the disordered monoamine regulation characteristic of this condition.

AB - We studied the non-specific responses of GH and PRL to gonadotropin releasing hormone (GnRH) in eleven male patients aged 18-30 in whom a diagnosis of acute schizophrenia was made according to Crow's criteria. GnRH administration was followed by a significant increase in plasma GH in five patients; plasma PRL increased in two patients. The two prolactin responders were also GH responders. Non-specific GH response was confirmed on repeated testing in two patients in whom GnRH stimulation was performed twice. During saline control, non-specific hormone responses were not observed. The abnormal hormone responses observed in acute schizophrenia are probably due to the disordered monoamine regulation characteristic of this condition.

UR - http://www.scopus.com/inward/record.url?scp=0022385456&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022385456&partnerID=8YFLogxK

U2 - 10.1016/0306-4530(85)90088-5

DO - 10.1016/0306-4530(85)90088-5

M3 - Article

C2 - 3911248

AN - SCOPUS:0022385456

VL - 10

SP - 481

EP - 484

JO - Psychoneuroendocrinology

JF - Psychoneuroendocrinology

SN - 0306-4530

IS - 4

ER -