Abstract
We studied the non-specific responses of GH and PRL to gonadotropin releasing hormone (GnRH) in eleven male patients aged 18-30 in whom a diagnosis of acute schizophrenia was made according to Crow's criteria. GnRH administration was followed by a significant increase in plasma GH in five patients; plasma PRL increased in two patients. The two prolactin responders were also GH responders. Non-specific GH response was confirmed on repeated testing in two patients in whom GnRH stimulation was performed twice. During saline control, non-specific hormone responses were not observed. The abnormal hormone responses observed in acute schizophrenia are probably due to the disordered monoamine regulation characteristic of this condition.
| Original language | English |
|---|---|
| Pages (from-to) | 481-484 |
| Number of pages | 4 |
| Journal | Psychoneuroendocrinology |
| Volume | 10 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1985 |
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ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
- Psychiatry and Mental health
- Biological Psychiatry
- Endocrine and Autonomic Systems
- Psychology(all)
Cite this
Gonadotropin releasing hormone elicits abnormal hormone responses in schizophrenia. / Cantalamessa, L.; Catania, A.; Silva, A.; Orsatti, A.; Motta, P.; Cazzullo, C. L.
In: Psychoneuroendocrinology, Vol. 10, No. 4, 1985, p. 481-484.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gonadotropin releasing hormone elicits abnormal hormone responses in schizophrenia
AU - Cantalamessa, L.
AU - Catania, A.
AU - Silva, A.
AU - Orsatti, A.
AU - Motta, P.
AU - Cazzullo, C. L.
PY - 1985
Y1 - 1985
N2 - We studied the non-specific responses of GH and PRL to gonadotropin releasing hormone (GnRH) in eleven male patients aged 18-30 in whom a diagnosis of acute schizophrenia was made according to Crow's criteria. GnRH administration was followed by a significant increase in plasma GH in five patients; plasma PRL increased in two patients. The two prolactin responders were also GH responders. Non-specific GH response was confirmed on repeated testing in two patients in whom GnRH stimulation was performed twice. During saline control, non-specific hormone responses were not observed. The abnormal hormone responses observed in acute schizophrenia are probably due to the disordered monoamine regulation characteristic of this condition.
AB - We studied the non-specific responses of GH and PRL to gonadotropin releasing hormone (GnRH) in eleven male patients aged 18-30 in whom a diagnosis of acute schizophrenia was made according to Crow's criteria. GnRH administration was followed by a significant increase in plasma GH in five patients; plasma PRL increased in two patients. The two prolactin responders were also GH responders. Non-specific GH response was confirmed on repeated testing in two patients in whom GnRH stimulation was performed twice. During saline control, non-specific hormone responses were not observed. The abnormal hormone responses observed in acute schizophrenia are probably due to the disordered monoamine regulation characteristic of this condition.
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UR - http://www.scopus.com/inward/citedby.url?scp=0022385456&partnerID=8YFLogxK
U2 - 10.1016/0306-4530(85)90088-5
DO - 10.1016/0306-4530(85)90088-5
M3 - Article
C2 - 3911248
AN - SCOPUS:0022385456
VL - 10
SP - 481
EP - 484
JO - Psychoneuroendocrinology
JF - Psychoneuroendocrinology
SN - 0306-4530
IS - 4
ER -