Grading of chemotherapy-induced peripheral neurotoxicity using the Total Neuropathy Scale

Guido Cavaletti; G. Bogliun; L. Marzorati; A. Zincone; M. Piatti; N. Colombo; G. Parma; A. Lissoni; F. Fei; S. Cundari; C. Zanna

Grading of chemotherapy-induced peripheral neurotoxicity using the Total Neuropathy Scale

Guido Cavaletti, G. Bogliun, L. Marzorati, A. Zincone, M. Piatti, N. Colombo, G. Parma, A. Lissoni, F. Fei, S. Cundari, C. Zanna

Istituto Europeo di Oncologia

Research output: Contribution to journal › Article › peer-review

Abstract

The authors compared clinically based neurotoxicity scales with the Total Neuropathy Scale, with the aim of improving the grading of the severity of chemotherapy-induced peripheral neuropathy (CIPN). The severity of CIPN was evaluated in a series of 60 women treated with cisplatin- and paclitaxel-based chemotherapy. A reduced version of TNS (TNSr) was also compared. The authors concluded that the TNS and TNSr can be used to assess the severity of CIPN effectively, and the results of this evaluation can be reliably correlated with the oncologic grading of sensory peripheral neurotoxicity.

Original language	English
Pages (from-to)	1297-1300
Number of pages	4
Journal	Neurology
Volume	61
Issue number	9
Publication status	Published - Nov 11 2003

ASJC Scopus subject areas

Neuroscience(all)

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title = "Grading of chemotherapy-induced peripheral neurotoxicity using the Total Neuropathy Scale",

abstract = "The authors compared clinically based neurotoxicity scales with the Total Neuropathy Scale, with the aim of improving the grading of the severity of chemotherapy-induced peripheral neuropathy (CIPN). The severity of CIPN was evaluated in a series of 60 women treated with cisplatin- and paclitaxel-based chemotherapy. A reduced version of TNS (TNSr) was also compared. The authors concluded that the TNS and TNSr can be used to assess the severity of CIPN effectively, and the results of this evaluation can be reliably correlated with the oncologic grading of sensory peripheral neurotoxicity.",

author = "Guido Cavaletti and G. Bogliun and L. Marzorati and A. Zincone and M. Piatti and N. Colombo and G. Parma and A. Lissoni and F. Fei and S. Cundari and C. Zanna",

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AU - Cavaletti, Guido

AU - Bogliun, G.

AU - Marzorati, L.

AU - Zincone, A.

AU - Piatti, M.

AU - Colombo, N.

AU - Parma, G.

AU - Lissoni, A.

AU - Fei, F.

AU - Cundari, S.

AU - Zanna, C.

PY - 2003/11/11

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N2 - The authors compared clinically based neurotoxicity scales with the Total Neuropathy Scale, with the aim of improving the grading of the severity of chemotherapy-induced peripheral neuropathy (CIPN). The severity of CIPN was evaluated in a series of 60 women treated with cisplatin- and paclitaxel-based chemotherapy. A reduced version of TNS (TNSr) was also compared. The authors concluded that the TNS and TNSr can be used to assess the severity of CIPN effectively, and the results of this evaluation can be reliably correlated with the oncologic grading of sensory peripheral neurotoxicity.

AB - The authors compared clinically based neurotoxicity scales with the Total Neuropathy Scale, with the aim of improving the grading of the severity of chemotherapy-induced peripheral neuropathy (CIPN). The severity of CIPN was evaluated in a series of 60 women treated with cisplatin- and paclitaxel-based chemotherapy. A reduced version of TNS (TNSr) was also compared. The authors concluded that the TNS and TNSr can be used to assess the severity of CIPN effectively, and the results of this evaluation can be reliably correlated with the oncologic grading of sensory peripheral neurotoxicity.

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