Grading of chemotherapy-induced peripheral neurotoxicity using the Total Neuropathy Scale

Guido Cavaletti, G. Bogliun, L. Marzorati, A. Zincone, M. Piatti, N. Colombo, G. Parma, A. Lissoni, F. Fei, S. Cundari, C. Zanna

Research output: Contribution to journalArticlepeer-review

Abstract

The authors compared clinically based neurotoxicity scales with the Total Neuropathy Scale, with the aim of improving the grading of the severity of chemotherapy-induced peripheral neuropathy (CIPN). The severity of CIPN was evaluated in a series of 60 women treated with cisplatin- and paclitaxel-based chemotherapy. A reduced version of TNS (TNSr) was also compared. The authors concluded that the TNS and TNSr can be used to assess the severity of CIPN effectively, and the results of this evaluation can be reliably correlated with the oncologic grading of sensory peripheral neurotoxicity.

Original languageEnglish
Pages (from-to)1297-1300
Number of pages4
JournalNeurology
Volume61
Issue number9
Publication statusPublished - Nov 11 2003

ASJC Scopus subject areas

  • Neuroscience(all)

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